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高维生存数据的分位数向前回归

Quantile forward regression for high-dimensional survival data.

作者信息

Lee Eun Ryung, Park Seyoung, Lee Sang Kyu, Hong Hyokyoung G

机构信息

Department of Statistics, Sungkyunkwan University, Seoul, 03063, Korea.

Department of Statistics and Probability, Michigan State University, East Lansing, MI, 48823, USA.

出版信息

Lifetime Data Anal. 2023 Oct;29(4):769-806. doi: 10.1007/s10985-023-09603-w. Epub 2023 Jul 2.

DOI:10.1007/s10985-023-09603-w
PMID:37393569
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12128792/
Abstract

Despite the urgent need for an effective prediction model tailored to individual interests, existing models have mainly been developed for the mean outcome, targeting average people. Additionally, the direction and magnitude of covariates' effects on the mean outcome may not hold across different quantiles of the outcome distribution. To accommodate the heterogeneous characteristics of covariates and provide a flexible risk model, we propose a quantile forward regression model for high-dimensional survival data. Our method selects variables by maximizing the likelihood of the asymmetric Laplace distribution (ALD) and derives the final model based on the extended Bayesian Information Criterion (EBIC). We demonstrate that the proposed method enjoys a sure screening property and selection consistency. We apply it to the national health survey dataset to show the advantages of a quantile-specific prediction model. Finally, we discuss potential extensions of our approach, including the nonlinear model and the globally concerned quantile regression coefficients model.

摘要

尽管迫切需要一个针对个人兴趣的有效预测模型,但现有的模型主要是为平均结果开发的,目标是普通人群。此外,协变量对平均结果的影响方向和大小在结果分布的不同分位数上可能不成立。为了适应协变量的异质性特征并提供一个灵活的风险模型,我们为高维生存数据提出了一种分位数向前回归模型。我们的方法通过最大化非对称拉普拉斯分布(ALD)的似然性来选择变量,并基于扩展贝叶斯信息准则(EBIC)推导最终模型。我们证明了所提出的方法具有确定筛选性质和选择一致性。我们将其应用于国家健康调查数据集,以展示分位数特定预测模型的优势。最后,我们讨论了我们方法的潜在扩展,包括非线性模型和全局关注的分位数回归系数模型。

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Quantile forward regression for high-dimensional survival data.高维生存数据的分位数向前回归
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本文引用的文献

1
Low-rank regression models for multiple binary responses and their applications to cancer cell-line encyclopedia data.用于多个二元响应的低秩回归模型及其在癌细胞系百科全书数据中的应用。
J Am Stat Assoc. 2024;119(545):202-216. doi: 10.1080/01621459.2022.2105704. Epub 2022 Sep 20.
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Quantile Regression for Survival Data.生存数据的分位数回归
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Consistent Estimation of Generalized Linear Models with High Dimensional Predictors via Stepwise Regression.通过逐步回归对具有高维预测变量的广义线性模型进行一致估计。
Entropy (Basel). 2020 Aug 31;22(9):965. doi: 10.3390/e22090965.
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Weight loss and BMI criteria in GLIM's definition of malnutrition is associated with postoperative complications following abdominal resections - Results from a National Quality Registry.GLIM 营养不良定义中的体重减轻和 BMI 标准与腹部切除术后的术后并发症相关 - 来自国家质量登记处的结果。
Clin Nutr. 2020 May;39(5):1593-1599. doi: 10.1016/j.clnu.2019.07.003. Epub 2019 Jul 20.
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Quantile regression for survival data in modern cancer research: expanding statistical tools for precision medicine.现代癌症研究中生存数据的分位数回归:拓展精准医学的统计工具
Precis Clin Med. 2019 Jun;2(2):90-99. doi: 10.1093/pcmedi/pbz007. Epub 2019 Jun 18.
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Building generalized linear models with ultrahigh dimensional features: A sequentially conditional approach.超高维特征的广义线性模型构建:一种序贯条件方法。
Biometrics. 2020 Mar;76(1):47-60. doi: 10.1111/biom.13122. Epub 2019 Nov 6.
7
Healthy lifestyle is inversely associated with mortality in cancer survivors: Results from the Third National Health and Nutrition Examination Survey (NHANES III).健康的生活方式与癌症幸存者的死亡率呈负相关:来自第三次全国健康和营养检查调查(NHANES III)的结果。
PLoS One. 2019 Jun 26;14(6):e0218048. doi: 10.1371/journal.pone.0218048. eCollection 2019.
8
Protein intake and the incidence of pre-diabetes and diabetes in 4 population-based studies: the PREVIEW project.蛋白质摄入与 4 项基于人群的研究中前驱糖尿病和糖尿病的发病情况:PREVIEW 项目。
Am J Clin Nutr. 2019 May 1;109(5):1310-1318. doi: 10.1093/ajcn/nqy388.
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Forward regression for Cox models with high-dimensional covariates.具有高维协变量的Cox模型的向前回归
J Multivar Anal. 2019 Sep;173:268-290. doi: 10.1016/j.jmva.2019.02.011. Epub 2019 Mar 5.
10
Variable screening via quantile partial correlation.通过分位数偏相关进行变量筛选。
J Am Stat Assoc. 2017;112(518):650-663. doi: 10.1080/01621459.2016.1156545. Epub 2017 Mar 30.