过敏和过敏反应概述。
Overview of Allergy and Anaphylaxis.
机构信息
Division of Emergency Medicine, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, 3333 Burnet Avenue, MLC 2008, Cincinnati, OH 45229-3039, USA.
Department of Allergy and Immunology, University of Hawaii, Kaiser Honolulu Clinic, 1010 Pensacola Street, Honolulu, HI 96814, USA; Department of Medicine, University of Hawaii, Kaiser Honolulu Clinic, 1010 Pensacola Street, Honolulu, HI 96814, USA.
出版信息
Immunol Allergy Clin North Am. 2023 Aug;43(3):435-451. doi: 10.1016/j.iac.2022.10.009.
Allergic reactions and anaphylaxis occur on a severity continuum from mild and self-limited to potentially life-threatening or fatal reactions. Anaphylaxis is typically a multiorgan phenomenon involving a broad range of effector cells and mediators. Emergency department visits for anaphylaxis are increasing, especially among children. There is a broad differential diagnosis for anaphylaxis, and the diagnosis of anaphylaxis can be aided by the use of the National Institutes of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network clinical diagnostic criteria. Risk factors for severe anaphylaxis include older age, delayed epinephrine administration, and cardiopulmonary comorbidities.
过敏反应和过敏反应是一个严重程度连续谱，从轻到自我限制到潜在的危及生命或致命反应不等。过敏反应通常是一种多器官现象，涉及广泛的效应细胞和介质。过敏反应的急诊就诊率正在上升，尤其是在儿童中。过敏反应的鉴别诊断范围很广，使用美国国立过敏和传染病研究所/食物过敏和过敏反应网络临床诊断标准可以帮助诊断过敏反应。严重过敏反应的危险因素包括年龄较大、肾上腺素延迟给药和心肺合并症。
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