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糖尿病妊娠中的胎儿监护。II. 无应激试验与缩宫素激惹试验

Fetal surveillance in diabetic pregnancy. II. The nonstress test versus the oxytocin challenge test.

作者信息

Olofsson P, Sjöberg N O, Solum T

出版信息

Acta Obstet Gynecol Scand. 1986;65(4):357-60. doi: 10.3109/00016348609157360.

DOI:10.3109/00016348609157360
PMID:3739648
Abstract

At the Department of Obstetrics and Gynecology, University of Lund, it has been the routine management in diabetic pregnancy to use both nonstress test (NST) and oxytocin challenge test (OCT) for fetal surveillance. The study material reported comprised 61 pregnant diabetics, 1,882 NSTs and 90 OCTs. Evaluations were made separately for the time interval 0-2 days antepartum, within 1 week antepartum, and all tests included. Predictive value, specificity and sensitivity were calculated for both the NSTs and the OCTs according to the following variables of neonatal outcome: Apgar scores at 1, 5 and 10 min, baby's first cry (or not) within 1 min of birth, pulmonary function, and metabolic balance. No perinatal deaths occurred. There were no statistically significant differences between the NSTs and OCTs in the antepartum time intervals 0-2 days and less than or equal to 1 week regarding any variable. When all tests were included, the OCT proved superior in that there were fewer falsely pathological tests, though biased by the fact that most of the NSTs evaluated were older than the oldest OCT in this context. Nevertheless, it is concluded that the OCT does not favor the NST for routine fetal surveillance in diabetic pregnancy.

摘要

在隆德大学妇产科,糖尿病妊娠的常规管理是同时使用无应激试验(NST)和缩宫素激惹试验(OCT)进行胎儿监护。报告的研究资料包括61例糖尿病孕妇、1882次NST和90次OCT。分别对产前0至2天、产前1周内以及所有纳入试验的时间间隔进行评估。根据新生儿结局的以下变量计算NST和OCT的预测值、特异性和敏感性:出生后1分钟、5分钟和10分钟的阿氏评分、出生后1分钟内婴儿的第一声啼哭(或无啼哭)、肺功能和代谢平衡。未发生围产期死亡。在产前0至2天和小于或等于1周的时间间隔内,NST和OCT在任何变量上均无统计学显著差异。当纳入所有试验时,OCT表现更优,因为其假阳性试验较少,不过由于在此背景下评估的大多数NST比最老的OCT更旧,存在一定偏差。尽管如此,得出的结论是,在糖尿病妊娠的常规胎儿监护中,OCT并不优于NST。

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Fetal surveillance in diabetic pregnancy. II. The nonstress test versus the oxytocin challenge test.糖尿病妊娠中的胎儿监护。II. 无应激试验与缩宫素激惹试验
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