Wan Sai, Wang Haoming, Ma Xiaoqing, Tan Yang, Liu Licheng, Li Fuli
Qingdao C1 Refinery Engineering Research Center, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, Shandong, China.
College of Chemistry and Chemical Engineering, Ocean University of China, Qingdao 266100, Shandong, China.
Sheng Wu Gong Cheng Xue Bao. 2023 Jun 25;39(6):2410-2429. doi: 10.13345/j.cjb.221004.
The current linear economy model relies on fossil energy and increases CO emissions, which contributes to global warming and environmental pollution. Therefore, there is an urgent need to develop and deploy technologies for carbon capture and utilization to establish a circular economy. The use of acetogens for C1-gas (CO and CO) conversion is a promising technology due to high metabolic flexibility, product selectivity, and diversity of the products including chemicals and fuels. This review focuses on the physiological and metabolic mechanisms, genetic and metabolic engineering modifications, fermentation process optimization, and carbon atom economy in the process of C1-gas conversion by acetogens, with the aim to facilitate the industrial scale-up and carbon negative production through acetogen gas fermentation.
当前的线性经济模式依赖化石能源并增加二氧化碳排放，这导致全球变暖和环境污染。因此，迫切需要开发和应用碳捕获与利用技术以建立循环经济。由于产乙酸菌具有高代谢灵活性、产物选择性以及包括化学品和燃料在内的产物多样性，利用产乙酸菌将C1气体（CO和CO₂）转化是一项很有前景的技术。本综述聚焦于产乙酸菌将C1气体转化过程中的生理和代谢机制、遗传和代谢工程改造、发酵过程优化以及碳原子经济性，旨在通过产乙酸菌气体发酵促进工业规模扩大和负碳生产。
