Pala Erdal, Melikoğlu Mehmet, Karaşahin Ömer, Alkan Melikoğlu Meltem
Department of Dermatology and Venerology, Atatürk University, Faculty of Medicine, Erzurum, Turkey.
Erzurum Regional Training and Research Hospital, Infectious Diseases Erzurum, Turkey.
Eurasian J Med. 2023 Jun;55(2):158-164. doi: 10.5152/eurasianjmed.2023.53.
OBJECTIVE: While the relationship between psoriatic arthritis and skin findings is well-known in patients with psoriasis, the relationship between psoriatic arthritis and nail involvement is less known. In this study, it was aimed to examine the frequency of association between nail involvement and psoriatic arthritis in patients with psoriasis. MATERIALS AND METHODS: Our study is a retrospective observational study. It was conducted with 250 regis- tered patients who applied to the dermatology polyclinic and clinic of our university hospital. The follow-up forms of the patients were scanned retrospectively and the findings were recorded. RESULTS: The average age of the 250 patients evaluated in this study was 39.62 ± 9.30, and 133 (53.2%) of them were women. The frequency of nail involvement in psoriasis patients was determined to be 36.8% (n=92) and the frequency of arthritis was determined to be 8.8% (n=22). Nail involvement was statisti- cally significantly more common in those with arthritis, and nail involvement was present in all of those with arthritis (P < .001). Nail involvement was significantly more common in those with only arthralgia (P < .001). A significantly higher average of nail psoriasis severity index was found in those with both joint and nail involvement compared to those with only nail involvement (P < .001). There was no statistically significant difference in terms of psoriasis area severity index average (P=.235). Proximal and distal interphalangeal arthralgia and sacroiliac arthralgia were found significantly more frequently in those with nail involvement than in those without nail involvement (respectively P = .007 and P < .001). There was no statistically signifi- cant relationship between nail involvement with the presence of arthritis and the clinical type (respectively P = .288 and P = .955). CONCLUSION: Joint involvement and nail involvement in patients with psoriasis are closely related, and we think that nail and joint involvement in psoriasis patients should be evaluated together.
目的：虽然银屑病患者中银屑病关节炎与皮肤表现之间的关系已为人熟知，但银屑病关节炎与指甲受累之间的关系却鲜为人知。本研究旨在调查银屑病患者中指甲受累与银屑病关节炎的关联频率。 材料与方法：我们的研究是一项回顾性观察研究。研究对象为250名到我校医院皮肤科门诊和病房就诊并登记的患者。对患者的随访表格进行回顾性扫描并记录相关发现。 结果：本研究评估的250例患者的平均年龄为39.62±9.30岁，其中133例（53.2%）为女性。银屑病患者中指甲受累的频率为36.8%（n=92），关节炎的频率为8.8%（n=22）。在患有关节炎的患者中，指甲受累在统计学上显著更常见，且所有患有关节炎的患者均有指甲受累（P<.001）。在仅有关节痛的患者中，指甲受累也显著更常见（P<.001）。与仅有指甲受累的患者相比，同时有关节和指甲受累的患者的指甲银屑病严重程度指数平均值显著更高（P<.001）。银屑病面积严重程度指数平均值方面无统计学显著差异（P=.235）。指甲受累的患者近端和远端指间关节痛及骶髂关节痛的发生率显著高于无指甲受累的患者（分别为P=.007和P<.001）。指甲受累与关节炎的存在及临床类型之间均无统计学显著关系（分别为P=.288和P=.955）。 结论：银屑病患者的关节受累与指甲受累密切相关，我们认为银屑病患者的指甲和关节受累应一起评估。
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