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硬化疗法联合痔动脉结扎术及黏膜固定术治疗Ⅱ、Ⅲ度痔疮的效果:一项为期4年的单中心经验。

Results of sclerotherapy and mucopexy with haemorrhoidal dearterialization in II and III degree haemorrhoids. A 4 years' single centre experience.

作者信息

Lobascio Pierluigi, Laforgia Rita, Pezzolla Angela

机构信息

Coloproctology Unit "Bari 2", Laparoscopic and Emergency Surgical Unit, Department of Emergency and Trasnsplantation of Organs, Hospital University of Bari, Bari, Italy.

出版信息

Front Surg. 2023 Jun 19;10:1151327. doi: 10.3389/fsurg.2023.1151327. eCollection 2023.

Abstract

INTRODUCTION

Haemorrhoidal disease (HD) affects a considerable portion of the adult population. The aim of this study is to confirm the safety and efficacy of the treatments and to report the long-term outcomes of Sclerotherapy (ST) and Mucopexy and Haemorrhoidal Dearterialization (MHD) performed over the last 4 years in a single tertiary centre. The secondary outcome is to evaluate the usefulness of both techniques and to demonstrate how those can be associated as a bridge to surgery.

MATERIALS AND METHODS

Patients affected by second-third-degree haemorrhoids and undergoing ST or non-Doppler guided MHD between 2018 and 2021 were enrolled. Safety and efficacy, recurrence rate, Haemorrhoid Severity Score (HSS) and pain resulting from both techniques were evaluated.

RESULTS

Out of 259 patients, 150 underwent ST. Further, 122 (81.3%) patients were male and 28 (18.7%) were female. The mean age was 50.8 (range 34-68) years. Most of the patients (103, 68.6%) were affected by second-degree HD, while 47 (31.4%) were affected by third-degree HD. The overall success rate was 83.3%. The median pre-operative HSS score was 3 (IQR 0-4,  = 0.04) and at 2 year the median HSS was 0 (IQR 0-1,  = 0.03). No intraoperative complications and no drug-related side effects occurred. The mean follow-up for ST was 2 years (range 1-4; SD ±0.88). MHD was performed on 109 patients. In detail, 80 patients (73.4%) were male while 29 patients (26.6%) were female. The mean age in this group was 51.3 (range 31-69). Further, 72 patients (66.1%) were affected by third-degree HD and 37 (33.9%) by second-degree HD. The median HSS score was 9 (IQR 8-10,  = 0.001) preoperatively two years after treatment was 0 (IQR 0-1,  = 0.004). Major complications occurred in three patients (2.75%). The overall success rate was 93.5% (second degree 89.2% vs. third degree 95.8%). The mean follow-up for MHD was 2 years (range 1-4; SD ±0.68).

CONCLUSIONS

The results confirm the usefulness of those techniques, which can be considered safe and easily repeatable procedures, with a low recurrence rate after 2 years of median follow-up.

摘要

引言

痔病(HD)影响着相当一部分成年人群。本研究的目的是确认治疗的安全性和有效性,并报告过去4年在单个三级中心进行硬化疗法(ST)、黏膜固定术和痔动脉结扎术(MHD)的长期结果。次要结果是评估这两种技术的实用性,并证明它们如何作为手术的桥梁联合应用。

材料与方法

纳入2018年至2021年间患有二至三度痔且接受ST或非多普勒引导下MHD治疗的患者。评估两种技术的安全性和有效性、复发率、痔严重程度评分(HSS)和疼痛情况。

结果

259例患者中,150例接受了ST治疗。此外患者中,122例(81.3%)为男性,28例(18.7%)为女性。平均年龄为50.8岁(范围34 - 68岁)。大多数患者(共103例,68.6%)患有二度HD,而47例(31.4%)患有三度HD。总体成功率为83.3%。术前HSS评分中位数为3(四分位间距0 - 4,P = 0.04),2年后HSS中位数为0(四分位间距0 - 1,P = 0.03)。未发生术中并发症和药物相关副作用。ST的平均随访时间为2年(范围1 - 4年;标准差±0.88)。109例患者接受了MHD治疗。具体而言,80例患者(73.4%)为男性,29例患者(26.6%)为女性。该组平均年龄为51.3岁(范围31 -

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ec2/10317504/f2d657e840c0/fsurg-10-1151327-g001.jpg

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