Noor Research Center for Ophthalmic Epidemiology, Noor Eye Hospital, Tehran, Iran.
Noor Ophthalmology Research Center, Noor Eye Hospital, Tehran, Iran.
Int Ophthalmol. 2023 Nov;43(11):3999-4009. doi: 10.1007/s10792-023-02804-0. Epub 2023 Jul 5.
To compare astigmatic correction among photorefractive keratectomy (PRK), femtosecond laser-assisted in situ keratomileusis (FS-LASIK), and small-incision lenticule extraction (SMILE).
This prospective study enrolled 157 eyes that underwent three procedures (59 PRK, 47 FS-LASIK, and 51 SMILE) for the treatment of myopia with low to high astigmatism (- 0.25 to - 4.50 D). Ocular residual astigmatism (ORA) was calculated by vector analysis using refractive (RA) and corneal astigmatism. Vector analysis results were compared in different procedures in the two RA groups (low ≤ 1.00 D and high > 1.00 D) at 3 and 12 months postoperatively.
There were no significant between-group differences in postoperative safety and efficacy outcomes (all P > 0.05). No significant differences were found in postoperative cylinders between all surgical groups (all p > 0.05), except for 3 months postoperative ORA in FS-LASIK (P = 0.004). At 12 months, 77%, 59.2%, and 50% of eyes attain emmetropia in the FS-LASIK, SMILE, and PRK groups, respectively. Vector analysis showed comparable values for surgical induced astigmatism, target induced astigmatism, mean error, and angle of error between groups at 12 months. Significant differences were observed only in the correction index and difference vector parameters in the astigmatic > 1.00 D group at 3 months (P < 0.001), and FS-LASIK was preferable.
One-year outcomes revealed that PRK, FS-LASIK, and SMILE were all equally effective in correcting myopic astigmatism. However, FS-LASIK demonstrated more favorable astigmatism correction in eyes with astigmatism > 1.00D in early postoperatively.
比较光折射性角膜切削术(PRK)、飞秒激光辅助原位角膜磨镶术(FS-LASIK)和小切口微透镜提取术(SMILE)治疗低至高散光近视的术后散光矫正效果。
本前瞻性研究纳入了 157 只接受了三种手术(59 只 PRK、47 只 FS-LASIK 和 51 只 SMILE)治疗低至高散光近视(-0.25 至-4.50 屈光度)的眼。通过使用屈光(RA)和角膜散光的矢量分析计算眼残余散光(ORA)。在术后 3 个月和 12 个月时,在两个 RA 组(低≤1.00 D 和高>1.00 D)中比较不同手术程序的矢量分析结果。
各组间术后安全性和疗效结果无显著差异(均 P>0.05)。除 FS-LASIK 在术后 3 个月的 ORA 外(P=0.004),所有手术组之间的术后散光柱均无显著差异(均 P>0.05)。在术后 12 个月时,FS-LASIK、SMILE 和 PRK 组分别有 77%、59.2%和 50%的眼达到正视。12 个月时,各组间手术诱导散光、目标诱导散光、平均误差和误差角的矢量分析值具有可比性。仅在术后 3 个月时,散光>1.00 D 组的矫正指数和差异向量参数有显著差异(P<0.001),且 FS-LASIK 更具优势。
一年的结果表明,PRK、FS-LASIK 和 SMILE 在矫正近视散光方面同样有效。然而,在术后早期,FS-LASIK 对散光>1.00 D 的眼的散光矫正效果更优。