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未分化多形性肉瘤(UPS)侵犯乳腺组织:一项病例报告研究。

Invasion of undifferentiated pleomorphic sarcoma (UPS) in breast tissue; a case report study.

作者信息

Anzali Babak Choobi, Goli Rasoul, Faraji Navid, Torabzadeh Aysan, Najafzad Zahra, Nikpey Shayan

机构信息

Department of Emergency Medicine, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran.

Department of Medical-Surgical Nursing, School of Nursing and Midwifery, Urmia University of Medical Sciences, Urmia, Iran.

出版信息

Int J Surg Case Rep. 2023 Jun;107:108307. doi: 10.1016/j.ijscr.2023.108307. Epub 2023 May 9.

Abstract

INTRODUCTION AND IMPORTANCE

Breast sarcomas are scarce, histologically heterogeneous with nonepithelial malignancies that originate from the connective tissue within the parenchyma of breast. They can develop primarily, after radio-therapy (RT), or secondary due to chronic condition, including metastatic cancers.

CASE PRESENTATION

The present case report concerns 58-year-old women which was unbeknown to her malignancy in the early stages, until the mass became substantial in size. Chemotherapy and also radiotherapy were not effective, and the growth of tumor could not be prevented which the patient eventually died, due to respiratory complications.

CLINICAL DISCUSSION

Breast sarcomas are categorized in very rare malignancies, and the mortality of these types of cancers are significantly high as they often are not diagnosed in early stages. Based on the location and condition of the malignant tumor, therapeutic methods considered as chemotherapy, radiotherapy, and surgery.

CONCLUSION

In advance stages of breast sarcoma, chemotherapy, radiotherapy, and even surgery cannot be effectual. Therefore, periodical evaluation of breast wellness by diagnostic methods are recommended to all adult women.

摘要

引言与重要性

乳腺肉瘤较为罕见,组织学上具有异质性,是起源于乳腺实质内结缔组织的非上皮性恶性肿瘤。它们可原发形成,也可在放疗后发生,或继发于慢性疾病,包括转移性癌症。

病例报告

本病例报告涉及一名58岁女性,早期她并未意识到自己患有恶性肿瘤,直到肿块变得很大。化疗和放疗均无效,无法阻止肿瘤生长,患者最终因呼吸并发症死亡。

临床讨论

乳腺肉瘤被归类为非常罕见的恶性肿瘤,这类癌症的死亡率显著较高,因为它们往往在早期未被诊断出来。根据恶性肿瘤的位置和状况,治疗方法包括化疗、放疗和手术。

结论

在乳腺肉瘤的晚期阶段,化疗、放疗甚至手术都可能无效。因此,建议所有成年女性通过诊断方法定期评估乳腺健康状况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f589/10206423/7fe7d124b367/gr1.jpg

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