School of Mental Health, Jining Medical University, Jining, 272013, China.
Teachers' Union, Jining Medical University, Jining, 272067, China.
Sci Rep. 2023 Jul 5;13(1):10910. doi: 10.1038/s41598-023-38103-y.
Stressful life events (SLEs) closely correlates with depressive symptoms. Although vulnerability-stress model suggests SLEs interacted with dysfunctional attitudes (DA) to predict depression, the mediation role of DA is poorly understood. Therefore, this study intended to investigate the mediating role of DA and the moderating role of sex between SLEs and self-reported depression. A cross-sectional survey was conducted with a sample of 7769 Chinese college students. Participants were assessed in terms of self-reported SLEs, DA and depression variables. Results showed that there were significant sex differences in both SLE and DA. DA mediated the association between SLE and self-reported depression. The moderated mediation model analysis showed that the interaction of SLEs and sex significantly predicted DA in mediator variable model and self-reported depression in dependent variable model. Results indicated that DA partially mediated the association between SLEs and self-reported depression, and sex moderates the association between SLEs and both DA and self-reported depression, which females have bigger changes of DA and depressive symptoms across low and high levels of SLEs than males.
生活应激事件（SLEs）与抑郁症状密切相关。虽然易损性-应激模型表明 SLEs 与功能失调的态度（DA）相互作用以预测抑郁，但 DA 的中介作用仍不清楚。因此，本研究旨在探讨 DA 的中介作用以及性别在 SLEs 和自我报告的抑郁之间的调节作用。采用横断面调查方法，对 7769 名中国大学生进行了调查。参与者评估了自我报告的 SLEs、DA 和抑郁变量。结果表明，SLE 和 DA 均存在显著的性别差异。DA 中介了 SLE 与自我报告的抑郁之间的关系。调节中介模型分析表明，SLEs 和性别的交互作用在中介变量模型中显著预测了 DA，在因变量模型中预测了自我报告的抑郁。结果表明，DA 部分中介了 SLEs 与自我报告的抑郁之间的关系，性别调节了 SLEs 与 DA 和自我报告的抑郁之间的关系，即女性在 SLEs 的高低水平上的 DA 和抑郁症状变化大于男性。
