肾上腺素能参与介导前列环素对离体大鼠心房的正性变力作用和变时作用。
An adrenergic participation subserving a positive inotropism and chonotropism of prostacyclin on isolated rat atria.
作者信息
Borda L S, Cangas L, Gimeno M F, Gimeno A L
出版信息
Experientia. 1979 Apr 15;35(4):529-30. doi: 10.1007/BF01922751.
PMID:374108
Abstract
The effects of prostacyclin (PGI2) on the contractile frequency and on the isometric developed tension of spontaneously beating or paced isolated rat atria were explored. PGI2 enhanced frequency and contractile tension, both effects being blocked by the presence of propranolol, or following a pretreatment with 6-OHDopamine.
摘要
研究了前列环素（PGI2）对自发搏动或起搏的离体大鼠心房收缩频率和等长收缩张力的影响。PGI2可提高频率和收缩张力，这两种效应均可被普萘洛尔阻断，或在6-羟基多巴胺预处理后被阻断。
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