Departmemt of Obstetrics and Perinatology, Medical University of Lublin, Lublin, Poland.
Med Sci Monit. 2023 Jul 7;29:e939919. doi: 10.12659/MSM.939919.
Eclampsia is the most serious pregnancy complication and one of the main causes of death of pregnant and delivering women. The mortality rate of young mothers is 5-20%, emphasizing the severity of this pregnancy-related disorder. Today many centers have only rare opportunities to see and deal with eclampsia cases; therefore, it is very important to bring this emergency medical condition to the attention of attending physicians. All patients with eclampsia, and after eclamptic seizures, should be treated in an intensive care unit. However, taking into account clinical realities, especially in developing countries, this is not always possible. It is necessary for all gynecologists-obstetricians to be fully prepared for eclampsia, although its occurrence is very rare. Drug treatment aims to stop eclampsia seizures and prevent reoccurrence of convulsions and complications. Magnesium sulphate is the drug of first choice used in treatment of eclampsia seizure, whereas treatment with the use of antihypertensive drugs and proper blood pressure control is one of the most important factors effectively reducing the risk of deaths or acute complications and poor pregnancy outcomes. The most urgent part of the treatment is the lifesaving procedure involving airways patency assessment, maintenance of breathing and blood circulation of the mother, securing an adequate oxygen level of the mother and thereby of the fetus, and prevention of injuries. This review aims to present an overview of the current prevalence, diagnosis, and management of eclampsia and the need for improved maternal care.
子痫是最严重的妊娠并发症之一,也是孕产妇死亡的主要原因之一。年轻母亲的死亡率为 5-20%,这强调了这种与妊娠相关的疾病的严重性。如今,许多中心很少有机会看到和处理子痫病例;因此,将这种紧急医疗状况提请主治医生注意非常重要。所有子痫患者,以及子痫发作后,都应在重症监护室接受治疗。然而,考虑到临床实际情况,尤其是在发展中国家,这并不总是可行的。所有妇产科医生都必须充分准备好应对子痫,尽管其发生的可能性非常小。药物治疗旨在停止子痫发作,并预防抽搐再次发作和并发症。硫酸镁是治疗子痫发作的首选药物,而使用降压药物进行治疗和适当控制血压是有效降低死亡风险或急性并发症和不良妊娠结局风险的最重要因素之一。治疗中最紧急的部分是救生程序,包括评估气道通畅性、维持母亲的呼吸和血液循环、确保母亲和胎儿有足够的氧气水平,并预防受伤。本综述旨在概述子痫的当前流行情况、诊断和管理,以及对改善产妇护理的需求。