Sakurai Y, Sugimoto S
Behav Brain Res. 1986 Jun;20(3):295-301. doi: 10.1016/0166-4328(86)90229-9.
While the rat was performing a go/no-go alternation task with a 10-s delay period, neuronal activity was recorded from electrodes chronically implanted in the prefrontal cortex (PFC) and the dorsomedial thalamus (DMT). In both PFC and DMT, neuronal activity during the delay period prior to a 'go' response was different from that prior to a 'no-go' response. The results suggest that during the delay period the PFC and DMT maintain a memory for the generation of the response. Furthermore, it was found that DMT neuronal activity in the delay period was different between correct and error trials. Therefore, the DMT may be primarily important in performing the alternation behavior.
当大鼠执行一个带有10秒延迟期的“去/不去”交替任务时，从长期植入前额叶皮层（PFC）和背内侧丘脑（DMT）的电极记录神经元活动。在PFC和DMT中，“去”反应之前延迟期的神经元活动与“不去”反应之前的不同。结果表明，在延迟期，PFC和DMT保持着对反应产生的记忆。此外，还发现正确试验和错误试验中延迟期的DMT神经元活动不同。因此，DMT在执行交替行为中可能主要起重要作用。
