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听觉皮层损伤对白化大鼠纯音声音定位的影响。

Effects of auditory cortical lesions on pure-tone sound localization by the albino rat.

作者信息

Kelly J B, Kavanagh G L

出版信息

Behav Neurosci. 1986 Aug;100(4):569-75. doi: 10.1037//0735-7044.100.4.569.

DOI:10.1037//0735-7044.100.4.569
PMID:3741608
Abstract

Two-choice and three-choice tests were used to evaluate the effects of bilateral auditory cortical lesions on pure-tone sound localization by the albino rat. Both tests required that animals approach a distant sound source to obtain water reinforcement. Stimuli were single noise and tone bursts, 65 ms in duration including 20-ms rise and fall times. Tone frequencies were 2, 4, 8, 16, and 32 kHz adjusted to 40 dB (SPL) above the rat's absolute threshold. Five animals were tested in the two-choice situation following bilateral ablation of auditory cortex. Some reduction in performance was observed relative to normals, but impairments were not severe. Similar results were obtained for 2 brain-damaged animals tested in the three-choice situation. Thus, the ability to localize sounds in space remained intact after complete destruction of auditory cortex, and there was no indication of a frequency-dependent deficit.

摘要

采用二选一和三选一测试来评估双侧听觉皮层损伤对白化大鼠纯音声音定位的影响。这两种测试都要求动物接近远处的声源以获取水作为强化物。刺激为单个噪声和音爆,持续时间65毫秒,包括20毫秒的上升和下降时间。音调频率为2、4、8、16和32千赫,调整为比大鼠绝对阈值高40分贝(声压级)。在双侧听觉皮层切除后,对五只动物进行了二选一测试。相对于正常动物,观察到表现有所下降,但损伤并不严重。对在三选一测试中测试的两只脑损伤动物也得到了类似的结果。因此,在听觉皮层完全破坏后,在空间中定位声音的能力仍然完好,并且没有频率依赖性缺陷的迹象。

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Effects of auditory cortical lesions on pure-tone sound localization by the albino rat.听觉皮层损伤对白化大鼠纯音声音定位的影响。
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