Fox P D, Khaw P T, McBride B W, McGill J I, Ward K A
Br J Ophthalmol. 1986 Aug;70(8):584-8. doi: 10.1136/bjo.70.8.584.
A sensitive enzyme linked immunosorbent assay (ELISA) was developed to evaluate the potential of herpes simplex virus (HSV) specific antibodies in the diagnosis of herpetic eye infection. The presence of HSV specific secretory IgA (sIgA) in tears was found to be diagnostic of infection. However, serum and tear HSV specific IgG and IgA were not considered reliable indicators of active infection.
开发了一种灵敏的酶联免疫吸附测定(ELISA)来评估单纯疱疹病毒(HSV)特异性抗体在诊断疱疹性眼部感染中的潜力。发现泪液中存在HSV特异性分泌型IgA(sIgA)可诊断感染。然而,血清和泪液中的HSV特异性IgG和IgA并不被认为是活动性感染的可靠指标。