单纯疱疹病毒特异性血清免疫球蛋白A：在原发性或复发性疱疹感染患者及健康成年人中的检测
Herpes simplex virus-specific serum immunoglobulin a: detection in patients with primary or recurrent herpes infections and in healthy adults.
作者信息
Friedman M G, Kimmel N
出版信息
Infect Immun. 1982 Jul;37(1):374-7. doi: 10.1128/iai.37.1.374-377.1982.
Abstract
A sensitive radioimmunoassay was used to determine levels of herpes simplex virus (HSV)-specific immunoglobulin A (IgA) in serial serum samples drawn from patients with primary HSV infections and from persons with recurrent HSV infections, and in single samples from 90 healthy adults. Significantly rising HSV IgA titers were detected in patients with primary infections, whereas those with recurrent infections had nonfluctuating titers. Sera of IgG-seropositive healthy adults were all positive for HSV-specific IgA without special pretreatment.
摘要
采用一种灵敏的放射免疫分析法，测定从原发性单纯疱疹病毒（HSV）感染患者、复发性HSV感染患者采集的系列血清样本，以及90名健康成年人的单份样本中HSV特异性免疫球蛋白A（IgA）的水平。在原发性感染患者中检测到HSV IgA滴度显著升高，而复发性感染患者的滴度无波动。未经特殊预处理的IgG血清反应阳性的健康成年人血清，HSV特异性IgA均呈阳性。
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