Department of Pharmacy, The Affiliated Hospital of Qingdao University, Qingdao 266003, China.
Department of Basic Medical, Qingdao Huanghai University, Qingdao 266427, China.
Biomed Pharmacother. 2023 Sep;165:115074. doi: 10.1016/j.biopha.2023.115074. Epub 2023 Jul 6.
Aging is usually considered a key risk factor associated with multiple diseases, such as neurodegenerative diseases, cardiovascular diseases and cancer. Furthermore, the burden of age-related diseases has become a global challenge. It is of great significance to search for drugs to extend lifespan and healthspan. Cannabidiol (CBD), a natural nontoxic phytocannabinoid, has been regarded as a potential candidate drug for antiaging. An increasing number of studies have suggested that CBD could benefit healthy longevity. Herein, we summarized the effect of CBD on aging and analyzed the possible mechanism. All these conclusions may provide a perspective for further study of CBD on aging.
衰老是与多种疾病相关的一个关键风险因素,如神经退行性疾病、心血管疾病和癌症。此外,与年龄相关的疾病负担已成为一个全球性挑战。寻找能够延长寿命和健康寿命的药物具有重要意义。大麻二酚(CBD)是一种天然无毒的植物大麻素,已被视为抗衰老的潜在候选药物。越来越多的研究表明,CBD 可能有益于健康长寿。在此,我们总结了 CBD 对衰老的影响,并分析了可能的机制。所有这些结论可能为进一步研究 CBD 对衰老的影响提供一个视角。