Williams K R, Blayney A W
Biomaterials. 1986 Jul;7(4):287-91. doi: 10.1016/0142-9612(86)90052-9.
The bioactive glass Ceravital is rapidly covered by a fibrous encapsulating layer when placed in the rat middle ear. In addition, the surface of the glass becomes gradually modified from purely a silicate to a phosphosilicate. It is suggested that this phosphosilicate layer acts as a reservoir for the gradual mineralization of the encapsulating collagenous fibrils, resulting eventually in the formation of a strong bony bond.
生物活性玻璃Ceravital植入大鼠中耳后,会迅速被一层纤维包裹层覆盖。此外,玻璃表面会逐渐从单纯的硅酸盐转变为磷硅酸盐。据推测,这层磷硅酸盐层充当了包裹性胶原纤维逐渐矿化的储存库,最终导致形成牢固的骨结合。