Williams K R, Blayney A W
Biomaterials. 1986 Jul;7(4):283-6. doi: 10.1016/0142-9612(86)90051-7.
Glassy carbon implants in the middle ear of the rat model appear well tolerated over periods of 6 months. The implants are rapidly covered with a fibrous capsule resulting in some bonding to the surrounding tissue. At a later stage (12 wk), further development of this bond takes place through growth of bone onto the implant surface from adjoining bone lamellae. No adverse tissue reactions were found in the histological sections produced.
在大鼠模型的中耳植入玻璃碳,在6个月的时间里似乎耐受性良好。植入物很快被纤维囊覆盖,导致与周围组织有一定程度的粘连。在后期阶段(12周),这种粘连会通过相邻骨板的骨生长到植入物表面而进一步发展。在所制作的组织学切片中未发现不良组织反应。