Bell Leila, van Gemert Caroline, Allard Nicole, Brink Anne, Chan Po-Lin, Cowie Benjamin, Hellard Margaret, Homer Caroline S E, Howell Jess, O'Connor Michelle, Hocking Jane
Burnet Institute, Melbourne, Australia.
Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia.
Lancet Reg Health West Pac. 2023 Apr 5;35:100740. doi: 10.1016/j.lanwpc.2023.100740. eCollection 2023 Jun.
The diverse geographic, demographic, and societal factors in the Pacific Island Countries and Territories (PICTs) have contributed to unique epidemiological patterns of HIV, syphilis, and hepatitis B. Transmission can be during pregnancy, at the time of birth or via breastfeeding for HIV, and can have long-term adverse outcomes. Given the similarities in prevention of mother-to-child transmission of these infections, coordinated interventions for triple elimination are used. This systematic review has evaluated the peer-reviewed literature, grey literature, and global databases to assess the availability of data to report against elimination targets in the WHO Regional Framework for the Triple Elimination of Mother-to-Child Transmission of HIV, Hepatitis B and Syphilis in Asia and the Pacific 2018-2030. The secondary objective is to report on progress towards these targets. The findings show that none of the PICTs are on track to achieve triple elimination by 2030. Amongst the limited publicly available indicator data, there is suboptimal coverage for most indicators. It is important that there is an increase in availability of and access to antenatal care, testing, and treatment for pregnant women. Increased efforts are needed to collect data on key indicators and integrate reporting into existing systems to avoid extra burden.
Leila Bell was supported by an Australian Government Research Training Program (RTP) Scholarship, Australia. Funding sources had no role in paper design, data collection, data analysis, interpretation, or writing of the paper.
太平洋岛国和领地（PICTs）多样的地理、人口和社会因素导致了艾滋病毒、梅毒和乙型肝炎独特的流行病学模式。艾滋病毒的传播可发生在孕期、分娩时或通过母乳喂养，并且可能产生长期不良后果。鉴于预防这些感染的母婴传播存在相似之处，因此采用了协调一致的干预措施来实现三重消除。本系统评价评估了同行评审文献、灰色文献和全球数据库，以评估是否有数据可用于报告《2018 - 2030年亚洲及太平洋地区艾滋病毒、乙型肝炎和梅毒母婴传播三重消除世卫组织区域框架》中的消除目标。次要目标是报告在实现这些目标方面取得的进展。研究结果表明，没有一个太平洋岛国和领地有望在2030年前实现三重消除。在有限的公开可用指标数据中，大多数指标的覆盖范围并不理想。增加孕妇产前护理、检测和治疗的可及性和可获得性非常重要。需要加大力度收集关键指标数据，并将报告纳入现有系统，以避免额外负担。
莱拉·贝尔得到了澳大利亚政府研究培训计划（RTP）奖学金的支持，澳大利亚。资金来源在论文设计、数据收集、数据分析、解释或论文撰写过程中没有发挥作用。
