Rizo Rivera Ginner Odorico, Valladares Marion Jose, Toledo Vargas Hildebrando M, Chavez Elibeth, Garcia de la Rocha Alejandro A, Urcuyo Hernandez Luis A, Meneses Mercado Jose Daniel
CardioCenter Clinic, Jinotega-Matagalpa, Nicaragua.
Ministerio de Salud, Nicaragua.
Int J Cardiol Cardiovasc Risk Prev. 2023 Jun 23;18:200192. doi: 10.1016/j.ijcrp.2023.200192. eCollection 2023 Sep.
Adverse cardiovascular events that arise in patients with established cardiovascular disease have prompted researchers to seek variables that can help estimate residual cardiovascular risk and aid in its reduction. In Latin-America, there is limited data assessing this type of risk.
Estimate residual cardiovascular risk in ambulatory patients diagnosed with Chronic Coronary Syndrome (CCS) using the SMART-Score scale seen at five clinics in Nicaragua; determine the prevalence of patients that achieve a serum LDL level of <55 mg/dL; and describe the use of statins in these patients.
A total of 145 participants previously diagnosed with CCS seen regularly in ambulatory visits were enrolled. A survey was completed, including epidemiological variables that allowed the calculation of a SMART score. Data analysis was conducted using SPSS version 21.0.
A 46.2% of participants were male, the average age was 68.7 years (11.4 SD), 91% had hypertension, 80.7% had a BMI ≥25. Under the SMART Score risk classification per Dorresteijn et al. the following risk distribution was found: 2.8% low, 31% moderate, 20% high, 13.1% very high and 33.1% extremely high. Per the risk classification of Kaasenbrood et al., 2.8% were in the 0-9% group, 31% in the 10-19%, 20% in 20-29% and 46.2% were in the ≥30% group. A 64.8% did not meet LDL goals.
There is an inadequate control of cLDL levels in patients with CCS, and the appropriate available therapeutic resources aren't being utilized. It is important to achieve a proper control of lipid levels in order to improve cardiovascular outcomes, despite currently being far from these goals.
已确诊心血管疾病患者出现的不良心血管事件促使研究人员寻找有助于估计残余心血管风险并协助降低该风险的变量。在拉丁美洲,评估这类风险的数据有限。
使用在尼加拉瓜五家诊所所采用的SMART-Score量表,估计门诊诊断为慢性冠状动脉综合征(CCS)患者的残余心血管风险;确定血清低密度脂蛋白(LDL)水平<55mg/dL患者的患病率;并描述这些患者中他汀类药物的使用情况。
共纳入145名之前确诊为CCS且定期门诊就诊的参与者。完成了一项调查,包括可用于计算SMART评分的流行病学变量。使用SPSS 21.0版进行数据分析。
46.2%的参与者为男性,平均年龄为68.7岁(标准差11.4),91%患有高血压,80.7%的体重指数(BMI)≥25。根据Dorresteijn等人的SMART评分风险分类,发现以下风险分布:低风险2.8%,中度风险31%,高风险20%,非常高风险13.1%,极高风险33.1%。根据Kaasenbrood等人的风险分类,2.8%属于0-9%组,31%属于10-19%组,20%属于20-29%组,46.2%属于≥30%组。64.8%未达到LDL目标。
CCS患者的非高密度脂蛋白胆固醇(cLDL)水平控制不足,且未利用适当的可用治疗资源。尽管目前离这些目标还很远,但为改善心血管结局实现脂质水平的适当控制很重要。