Cummins P, Russell G
Comp Biochem Physiol B. 1986;84(3):343-8. doi: 10.1016/0305-0491(86)90087-8.
An SDS-electrophoretic comparison of atrial and ventricular myosin light chain isotypes was performed in mouse, rat, rabbit, dog, pig, rhesus monkey, baboon, human and cow heart. Light chains 1 and 2 in atria and ventricles differed in all species with the possible exception of the rhesus monkey. Relative migration of atrial and ventricular LC-2 isotypes was similar in all species but LC-1 isotypes varied in relative migration rates suggesting increased primary sequence heterogeneity. Order of migration was VLC-1 less than ALC-1 less than ALC-2 less than VLC-2 in mouse, rat, rabbit, dog, baboon and cow and ALC-1 less than VLC-1 less than ALC-2 less than VLC-2 in pig and human heart. No obvious relationship existed between electrophoretic pattern and phylogenetic evolution.
对小鼠、大鼠、兔、犬、猪、恒河猴、狒狒、人及牛的心脏进行了心房和心室肌球蛋白轻链同型的SDS电泳比较。除恒河猴外，所有物种心房和心室中的轻链1和轻链2均有差异。所有物种中心房和心室LC-2同型的相对迁移率相似，但LC-1同型的相对迁移率有所不同，提示一级序列异质性增加。在小鼠、大鼠、兔、犬、狒狒和牛的心脏中，迁移顺序为VLC-1 < ALC-1 < ALC-2 < VLC-2；在猪和人的心脏中，迁移顺序为ALC-1 < VLC-1 < ALC-2 < VLC-2。电泳图谱与系统发育进化之间不存在明显关系。
