人心室中的胎儿肌球蛋白轻链
Foetal myosin light chain in human ventricle.
作者信息
Cummins P, Price K M, Littler W A
出版信息
J Muscle Res Cell Motil. 1980 Sep;1(3):357-66. doi: 10.1007/BF00711936.
PMID:7229026
Abstract
Myosin light chain subunits from adult human atria and ventricle were characterized by two-dimensional gel electrophoresis. Atrial (ALC-1 and ALC-2) differed from ventricular (VLC-1 and VLC-2) light chains. Foetal (18--21 week) ventricle contained VLC-1 plus a foetal light chain (FLC-1) which could not be distinguished from adult ALC-1. Myosin FLC-1 was gradually lost from the ventricle and replaced by VLC-1 during foetal development and in the immediate postnatal period.
摘要
通过二维凝胶电泳对来自成年人心房和心室的肌球蛋白轻链亚基进行了表征。心房（ALC-1和ALC-2）轻链与心室（VLC-1和VLC-2）轻链不同。胎儿（18 - 21周）心室含有VLC-1以及一种无法与成年ALC-1区分的胎儿轻链（FLC-1）。在胎儿发育期间和出生后不久，肌球蛋白FLC-1逐渐从心室中消失，并被VLC-1取代。
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