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人心室中的胎儿肌球蛋白轻链

Foetal myosin light chain in human ventricle.

作者信息

Cummins P, Price K M, Littler W A

出版信息

J Muscle Res Cell Motil. 1980 Sep;1(3):357-66. doi: 10.1007/BF00711936.

DOI:10.1007/BF00711936
PMID:7229026
Abstract

Myosin light chain subunits from adult human atria and ventricle were characterized by two-dimensional gel electrophoresis. Atrial (ALC-1 and ALC-2) differed from ventricular (VLC-1 and VLC-2) light chains. Foetal (18--21 week) ventricle contained VLC-1 plus a foetal light chain (FLC-1) which could not be distinguished from adult ALC-1. Myosin FLC-1 was gradually lost from the ventricle and replaced by VLC-1 during foetal development and in the immediate postnatal period.

摘要

通过二维凝胶电泳对来自成年人心房和心室的肌球蛋白轻链亚基进行了表征。心房（ALC-1和ALC-2）轻链与心室（VLC-1和VLC-2）轻链不同。胎儿（18 - 21周）心室含有VLC-1以及一种无法与成年ALC-1区分的胎儿轻链（FLC-1）。在胎儿发育期间和出生后不久，肌球蛋白FLC-1逐渐从心室中消失，并被VLC-1取代。

相似文献

1
Foetal myosin light chain in human ventricle.人心室中的胎儿肌球蛋白轻链
J Muscle Res Cell Motil. 1980 Sep;1(3):357-66. doi: 10.1007/BF00711936.
2
Isolation of cardiac myosin light-chain isotypes by chromatofocusing. Comparison of human cardiac atrial light-chain 1 and foetal ventricular light-chain 1.通过聚焦色谱法分离心肌肌球蛋白轻链同工型。人心脏心房轻链1与胎儿心室轻链1的比较。
Eur J Biochem. 1985 Apr 1;148(1):135-43. doi: 10.1111/j.1432-1033.1985.tb08817.x.
3
Myosin isoenzymes in human hypertrophic hearts. Shift in atrial myosin heavy chains and in ventricular myosin light chains.人类肥厚型心脏中的肌球蛋白同工酶。心房肌球蛋白重链和心室肌球蛋白轻链的变化。
Eur Heart J. 1984 Dec;5 Suppl F:85-93. doi: 10.1093/eurheartj/5.suppl_f.85.
4
Myosin P-light chain isoenzymes in the human heart: evidence for diphosphorylation of the atrial P-LC form.人心脏中的肌球蛋白P轻链同工酶：心房P-LC形式双磷酸化的证据。
Basic Res Cardiol. 1989 May-Jun;84(3):298-305. doi: 10.1007/BF01907977.
5
Atrial and ventricular myosins from human hearts. I. Isoenzyme distribution during development and in the adult.人类心脏的心房和心室肌球蛋白。I. 发育过程中和成人阶段的同工酶分布
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6
A comparison of myosin light chain subunits in the atria and ventricles of mammals.哺乳动物心房和心室中肌球蛋白轻链亚基的比较。
Comp Biochem Physiol B. 1986;84(3):343-8. doi: 10.1016/0305-0491(86)90087-8.
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[The topographic characteristics and changes in the ontogeny of light-chain myosin in the human myocardium].[人心肌中轻链肌球蛋白的拓扑学特征及个体发育变化]
Ontogenez. 1990 Mar-Apr;21(2):218-22.
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Basic Res Cardiol. 1983 Nov-Dec;78(6):671-8. doi: 10.1007/BF01907214.

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