National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
NHC Key Laboratory of Trace Element Nutrition, National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
Nutrients. 2023 Apr 29;15(9):2146. doi: 10.3390/nu15092146.
The current study is to explore the association of the Chinese visceral adiposity index (CVAI) with hypertension, and to compare the predictive power of different adiposity indexes regarding hypertension among Chinese adults aged over 45 years. A total of 99,201 participants aged over 45 years from the China Nutrition and Health Surveillance 2015-2017 were included in this study. Multivariate adjusted logistic regression was used to calculate the odds ratio (OR) and 95% confidence interval (CI) of hypertension. Multivariate adjusted restricted cubic spline analyses were applied to explore the association of adiposity indexes with hypertension. Receiver operating characteristic (ROC) analyses were used to compare the predictive powers of different adiposity indexes of hypertension. All eight adiposity indexes included in this study were positively associated with hypertension. Compared with those in the lowest quartile of the CVAI, the participants in the highest quartile showed a significantly higher risk of hypertension (OR = 3.70, 95% CI = 3.54-3.86) after multiple adjustments. The ROC analyses suggested that the CVAI was the strongest predictor of hypertension compared to other adiposity indexes in both genders. The findings supported that the CVAI could serve as a reliable and cost-effective method for early identifying hypertension risk.
本研究旨在探讨中国内脏脂肪指数(CVAI)与高血压的相关性,并比较不同肥胖指数对中国 45 岁以上成年人高血压的预测能力。本研究共纳入了来自 2015-2017 年中国营养与健康监测的 99201 名 45 岁以上的参与者。采用多变量调整的逻辑回归计算高血压的比值比(OR)和 95%置信区间(CI)。采用多变量调整的限制性立方样条分析探讨肥胖指数与高血压的相关性。采用受试者工作特征(ROC)分析比较不同肥胖指数预测高血压的能力。本研究纳入的 8 种肥胖指数均与高血压呈正相关。与 CVAI 最低四分位数的参与者相比,经过多次调整后,CVAI 最高四分位数的参与者发生高血压的风险显著更高(OR=3.70,95%CI=3.54-3.86)。ROC 分析表明,在男性和女性中,CVAI 是预测高血压最强的指标,优于其他肥胖指数。这些发现支持 CVAI 可作为一种可靠且具有成本效益的方法,用于早期识别高血压风险。