Campbell W L, Schultz J C
Gastrointest Radiol. 1986;11(3):218-22. doi: 10.1007/BF02035077.
Using cineradiography, we studied esophageal peristalsis in patients with suspected systemic sclerosis and related diseases, and in patients without known esophageal disease who had been referred for upper gastrointestinal series. Patterns of peristaltic abnormality were identified, and specificity and sensitivity values calculated. Esophageal aperistalsis was 100% specific, and consistently weak peristalsis after all, swallows was 88% specific for systemic sclerosis. Specificity decreased to 70% in patients over age 60. Abnormal peristalsis after some, but not all, swallows had only 52% specificity. Consistently abnormal peristalsis (absent or diminished) was 67% sensitive for scleroderma. Although a high sensitivity value (87%) for cineradiography can be obtained by considering any peristaltic abnormality as a sign of scleroderma, this is achieved at the price of an undesirably high number of false positives (specificity 40%).
我们运用电影荧光摄影术，研究了疑似系统性硬化症及相关疾病患者以及因上消化道造影而转诊的无已知食管疾病患者的食管蠕动情况。确定了蠕动异常模式，并计算了特异性和敏感性值。食管无蠕动具有100%的特异性，而所有吞咽动作后蠕动持续减弱对系统性硬化症的特异性为88%。60岁以上患者的特异性降至70%。部分而非全部吞咽动作后出现的异常蠕动特异性仅为52%。持续异常蠕动（无或减弱）对硬皮病的敏感性为67%。虽然将任何蠕动异常视为硬皮病的征象可使电影荧光摄影术获得较高的敏感性值（87%），但这是以出现数量多得不理想的假阳性（特异性40%）为代价的。
