Biological activity of benzo[e]pyrene. An assessment based on mutagenic activities and metabolic profiles of the polycyclic hydrocarbon and its derivatives.
作者信息
Wood A W, Levin W, Thakker D R, Yagi H, Chang R L, Ryan D E, Thomas P E, Dansette P M, Whittaker N, Turujman S, Lehr R E, Kumar S, Jerina D M, Conney A H
出版信息
J Biol Chem. 1979 Jun 10;254(11):4408-15.
PMID:374411
Abstract
摘要
相似文献
1
2
Characterization of dog hepatic drug-metabolizing enzymes and resultant effects on benzo[a]pyrene metabolite pattern and mutagenicity.犬肝脏药物代谢酶的特性及其对苯并[a]芘代谢产物模式和致突变性的影响
Drug Metab Dispos. 1980 May-Jun;8(3):121-6.
3
Metabolism of benzo(a)pyrene and benzo (a)pyrene derivatives to mutagenic products by highly purified hepatic microsomal enzymes.通过高度纯化的肝微粒体酶将苯并(a)芘和苯并(a)芘衍生物代谢为致突变产物。
J Biol Chem. 1976 Aug 25;251(16):4882-90.
4
Metabolism of the mutagenic environmental pollutant, 6-nitrobenzo[a]pyrene: metabolic activation via ring oxidation.
Biochem Biophys Res Commun. 1982 Apr 14;105(3):1037-43. doi: 10.1016/0006-291x(82)91074-9.
5
The role of cytochrome P-450 forms in 2-aminoanthracene and benz[alpha]pyrene mutagenesis.细胞色素P - 450同工酶在2 - 氨基蒽和苯并[a]芘诱变中的作用。
Biochem Biophys Res Commun. 1979 Jul 12;89(1):195-201. doi: 10.1016/0006-291x(79)90963-x.
6
The metabolism of drugs and carcinogens in isolated subcellular fractions of Drosophila melanogaster. I. Activation of vinyl chloride, 2-aminoanthracene and benzo[a]pyrene as measured by mutagenic effects in Salmonella typhimurium.黑腹果蝇分离亚细胞组分中药物和致癌物的代谢。I. 以鼠伤寒沙门氏菌中的诱变效应测定氯乙烯、2-氨基蒽和苯并[a]芘的活化作用。
Chem Biol Interact. 1981 Mar 1;34(2):129-43. doi: 10.1016/0009-2797(81)90126-5.
7
High mutagenic potency of several polycyclic aromatic hydrocarbons induced by liver postmitochondrial fractions from control and xenobiotic-treated immature carp.来自对照和经外源化合物处理的未成熟鲤鱼的肝脏线粒体后组分诱导的几种多环芳烃的高致突变性。
Mutat Res. 1983 Aug;118(3):177-89. doi: 10.1016/0165-1218(83)90141-6.
8
[Mutagenic action of benz(a)pyrene and its metabolites in the in vitro Salmonella typhimurium-microsomes test system].[苯并(a)芘及其代谢产物在鼠伤寒沙门氏菌-微粒体体外试验系统中的致突变作用]
Biull Eksp Biol Med. 1980 Aug;90(8):208-10.
9
Inhibition of benzo(a)pyrene and benzo(a)pyrene 7,8-dihydrodiol metabolism by benzo(a)pyrene quinones.苯并(a)芘醌对苯并(a)芘和苯并(a)芘7,8-二氢二醇代谢的抑制作用。
Cancer Res. 1979 Oct;39(10):4123-9.
引用本文的文献
1
Anabasis setifera leaf extract from arid habitat: A treasure trove of bioactive phytochemicals with potent antimicrobial, anticancer, and antioxidant properties.干旱生境下的沙生霸王根叶提取物：富含生物活性植物化学成分的宝库，具有强大的抗菌、抗癌和抗氧化特性。
PLoS One. 2024 Oct 25;19(10):e0310298. doi: 10.1371/journal.pone.0310298. eCollection 2024.
2
The carcinogen benzo(e)pyrene is metabolized by DM15 cells without an uncoupling effect on their gap junctions.致癌物苯并（e）芘可被DM15细胞代谢，且对其间隙连接无解偶联作用。
Cell Biol Toxicol. 1993 Apr-Jun;9(2):131-40. doi: 10.1007/BF00757575.
3
Metabolic conversion of dibenz[a,h]anthracene (+/-)trans-1,2-dihydrodiol and chrysene (+/-)trans-3,4-dihydrodiol to vicinal dihydrodiol epoxides.二苯并[a,h]蒽（±）反式-1,2-二氢二醇和屈（±）反式-3,4-二氢二醇向邻位二氢二醇环氧化物的代谢转化。
Proc Natl Acad Sci U S A. 1981 Jul;78(7):4270-3. doi: 10.1073/pnas.78.7.4270.
Zotero 插件