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一项前瞻性、随机、单盲对照试验,比较超声与神经刺激器引导用于门诊上肢手术的肌间沟阻滞。

A prospective, randomised, single-blinded controlled trial comparing ultrasound versus nerve stimulator guidance for interscalene block for ambulatory upper limb surgeries.

作者信息

Khanna Sangeeta, Gupta Rama, Gupta Vivek, Gupta Tarun, Singh A K

机构信息

Senior Adviser (Anaesthesia), Military Hospital Kirkee, Pune, India.

Classified Specialist (Anaesthesiology), Military Hospital Kota, Rajasthan, India.

出版信息

Med J Armed Forces India. 2023 Jul-Aug;79(4):399-408. doi: 10.1016/j.mjafi.2022.01.003. Epub 2022 Apr 2.

Abstract

BACKGROUND

Interscalene block is usually performed using either ultrasound (US) or nerve stimulator (NS) guidance. This single-blinded, prospective, randomised study was performed to find out whether US was able to offer distinct advantages over conventional NS guidance.

METHODS

100 patients in the American Society of Anaesthesiology (ASA) physical status I to III, aged 18-70 years were randomised into US guided or NS guided group for interscalene block with 15 ml 0.5% bupivacaine and 5 ml 2% lignocaine. Patients were premedicated with midazolam 0.03 mg/kg (maximum 2 mg) and fentanyl 2 mcg/kg (max 100 mcg) was used as rescue analgesia.

RESULT

Mean time of onset of sensory block in the NS group was 6.2 min (3.1), the US group 4.7 min (1.1), p value (<0.001). Mean duration of post-operative analgesia in NS group 323.6 min (98.6), US group 558.6 min (144.3), (p < 0.001). Mean time for performance of block NS Group 7.3 min (2.0), and in the US group 4.9 min (1.3), (p < 0.001). Number of needle passes NS group 1.7(0.9), US group 1.3 (1.0), (p < 0.005). Total cost per surgery with NS was Rs 363.10 less than in the US-guided block. Incremental cost effectiveness ratio for ultrasound group for onset of block was Rs -242.07, Rs 92.0 for duration of block and Rs -151.29 for time for performance of block. No incident of post-operative neurological complications seen in either group.

CONCLUSION

Ultrasound use offers faster onset, longer duration of block, reduces time for performance of blocks with comparable complication rates. For most of the measured parameters it was superior but more costly than nerve stimulator for directly measured costs.

摘要

背景

肌间沟阻滞通常在超声(US)或神经刺激器(NS)引导下进行。本单盲、前瞻性、随机研究旨在确定超声引导相较于传统神经刺激器引导是否具有明显优势。

方法

100例美国麻醉医师协会(ASA)身体状况分级为I至III级、年龄在18至70岁的患者被随机分为超声引导组或神经刺激器引导组,接受15毫升0.5%布比卡因和5毫升2%利多卡因的肌间沟阻滞。患者术前使用咪达唑仑0.03毫克/千克(最大2毫克)进行预处理,芬太尼2微克/千克(最大100微克)用作补救镇痛。

结果

神经刺激器组感觉阻滞的平均起效时间为6.2分钟(3.1),超声组为4.7分钟(1.1),p值(<0.001)。神经刺激器组术后镇痛的平均持续时间为323.6分钟(98.6),超声组为558.6分钟(144.3),(p <0.001)。神经刺激器组进行阻滞的平均时间为7.3分钟(2.0),超声组为4.9分钟(1.3),(p <0.001)。神经刺激器组进针次数为1.7(0.9),超声组为1.3(1.0),(p <0.005)。神经刺激器引导下每次手术的总成本比超声引导下少363.10卢比。超声组阻滞起效的增量成本效果比为-242.07卢比,阻滞持续时间为92.0卢比,进行阻滞的时间为-151.29卢比。两组均未出现术后神经并发症。

结论

使用超声可使阻滞起效更快、持续时间更长,减少进行阻滞的时间,且并发症发生率相当。对于大多数测量参数,超声引导优于神经刺激器引导,但直接测量成本显示其成本更高。

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