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一例急性硒(亚硒酸)中毒尸检病例及人体组织中的硒含量

An autopsy case of acute selenium (selenious acid) poisoning and selenium levels in human tissues.

作者信息

Matoba R, Kimura H, Uchima E, Abe T, Yamada T, Mitsukuni Y, Shikata I

出版信息

Forensic Sci Int. 1986 Jun;31(2):87-92. doi: 10.1016/0379-0738(86)90192-1.

DOI:10.1016/0379-0738(86)90192-1
PMID:3744207
Abstract

A case of fatal suicidal ingestion of "Super Blue (Gun Blue)" (gun-blueing) is presented. Post-mortem examination of the patient revealed pulmonary edema with pleural effusion and congestion of the kidney. Necrosis of proximal tubules was found in the kidney by histological examination. "Super Blue" contains 4% selenious acid and 2.5% cupric sulfate in HCl. Levels of selenium and copper in tissues of the toxic case and normal individuals were determined. The selenium levels of tissues of the patient were 9-90-fold higher than that of normal subjects, whereas concentrations of copper were about 2-fold compared to that of control levels. The highest levels of selenium in the tissues of the patient were found in the lung, kidney and stomach contents.

摘要

本文报告一例因摄入“超级蓝(枪蓝)”(枪支发蓝剂)自杀致死的病例。对该患者进行的尸检显示有肺水肿、胸腔积液以及肾脏充血。通过组织学检查发现肾脏近端小管坏死。“超级蓝”在盐酸中含有4%的亚硒酸和2.5%的硫酸铜。测定了该中毒病例及正常个体组织中的硒和铜含量。患者组织中的硒含量比正常受试者高9至90倍,而铜浓度约为对照水平的2倍。患者组织中硒含量最高的部位是肺、肾和胃内容物。

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