Department of Nursing, Universitat de València, Av. Menendez Pelayo 19, 46010, Valencia, Spain.
Frailty and Cognitive Impairment Research Group (FROG), University of Valencia, Menéndez I Pelayo, 19, 46010, Valencia, Spain.
Aging Clin Exp Res. 2023 Oct;35(10):2069-2079. doi: 10.1007/s40520-023-02488-7. Epub 2023 Jul 13.
Health-related quality of life (HRQoL) may be impaired in the presence of sarcopenia. Since a specific quality of life questionnaire became available for sarcopenia (SarQol), cutoffs to screen for this condition have been proposed, prompting the need to assess them in different populations. Due to the lack of consensus on diagnostic criteria, the tool has not yet been analyzed in screening for sarcopenic obesity.
Our aim is to measure the SarQoL's metric properties and establish a cutoff in QoL assessments that could be used along the diagnostic pathway for sarcopenia and sarcopenic obesity in community-dwelling older women.
This cross-sectional study assessed women aged ≥ 70 years using the SarQol, sarcopenia criteria (EWGSOP2) and sarcopenic obesity criteria (ESPEN/EASO). Cutoffs for the SarQol were defined with a receiver-operating characteristics (ROC) curve, and sensitivity and specificity were analyzed.
Of the 95 included women (mean age 76.0 years, standard deviation [SD] 5.7), 7.3% (n = 7) were classified as having sarcopenic obesity, 22.1% (n = 21) as having sarcopenia, and 70.5% (n = 67) as not having sarcopenia. The total SarQol score was higher in women without sarcopenia (66.5 SD 16.2) versus those with sarcopenia (56.6 SD 15.6) and sarcopenic obesity (45.1 SD 7.9). A cutoff of ≤ 60 points is proposed for sarcopenia screening (area under the ROC curve [AUC] 0.67; 95% confidence interval [CI] 0.53-0.80; sensitivity 61.9%; specificity 62%), and ≤ 50 points for sarcopenic obesity (AUC 0.85; 95% CI 0.74-0.95; sensitivity 71.4%; specificity 76.9%).
Quality of life is compromised in women with sarcopenia and especially in those with sarcopenic obesity. The SarQol could be useful in screening for these conditions, providing insight into health-related quality of life in older people with sarcopenia.
存在肌少症时，健康相关生活质量（HRQoL）可能受损。由于出现了一种专门用于肌少症的生活质量问卷（SarQol），因此提出了用于筛查这种情况的截止值，这促使我们需要在不同人群中评估这些截止值。由于缺乏对诊断标准的共识，该工具尚未在筛查肌少症性肥胖症中进行分析。
我们旨在测量 SarQol 的度量属性，并确定可用于社区居住的老年女性肌少症和肌少症性肥胖症诊断途径的生活质量评估中的截止值。
本横断面研究使用 SarQol、肌少症标准（EWGSOP2）和肌少症性肥胖标准（ESPEN/EASO）评估了年龄≥70 岁的女性。使用接收器操作特征（ROC）曲线定义 SarQol 的截止值，并分析了敏感性和特异性。
在纳入的 95 名女性中（平均年龄 76.0 岁，标准差 [SD] 5.7），7.3%（n=7）被归类为肌少症性肥胖症，22.1%（n=21）被归类为肌少症，70.5%（n=67）没有肌少症。无肌少症的女性 SarQol 总分（66.5，SD 16.2）高于肌少症（56.6，SD 15.6）和肌少症性肥胖症（45.1，SD 7.9）的女性。建议将≤60 分作为肌少症筛查的截止值（ROC 曲线下面积 [AUC] 0.67；95%置信区间 [CI] 0.53-0.80；敏感性 61.9%；特异性 62%），将≤50 分作为肌少症性肥胖症的截止值（AUC 0.85；95% CI 0.74-0.95；敏感性 71.4%；特异性 76.9%）。
肌少症女性的生活质量受损，尤其是肌少症性肥胖症女性。SarQol 可用于筛查这些疾病，为肌少症老年人的健康相关生活质量提供见解。
