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Chimeric antibodies with 17-1A-derived variable and human constant regions.

作者信息

Sun L K, Curtis P, Rakowicz-Szulczynska E, Ghrayeb J, Morrison S L, Chang N, Koprowski H

出版信息

Hybridoma. 1986 Jul;5 Suppl 1:S17-20.

PMID:3744381
Abstract
摘要

相似文献

1
Chimeric antibodies with 17-1A-derived variable and human constant regions.具有源自17-1A的可变区和人恒定区的嵌合抗体。
Hybridoma. 1986 Jul;5 Suppl 1:S17-20.
2
Characterization of a mouse/human chimeric monoclonal antibody (17-1A) to a colon cancer tumor-associated antigen.一种针对结肠癌肿瘤相关抗原的小鼠/人嵌合单克隆抗体(17-1A)的特性分析
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3
Chimeric antibody with human constant regions and mouse variable regions directed against carcinoma-associated antigen 17-1A.具有人恒定区和针对癌相关抗原17-1A的小鼠可变区的嵌合抗体。
Proc Natl Acad Sci U S A. 1987 Jan;84(1):214-8. doi: 10.1073/pnas.84.1.214.
4
Comparative sequence analysis of CO17-1A antigen-specific monoclonal antibodies.CO17-1A抗原特异性单克隆抗体的比较序列分析。
Hybridoma. 1986 Jul;5 Suppl 1:S11-6.
5
Human antibody genes. Evolutionary and molecular genetic perspectives.人类抗体基因。进化与分子遗传学视角。
Adv Hum Genet. 1983;13:113-47.
6
Chimeric human antibody molecules: mouse antigen-binding domains with human constant region domains.嵌合人源抗体分子:具有人恒定区结构域的小鼠抗原结合结构域。
Proc Natl Acad Sci U S A. 1984 Nov;81(21):6851-5. doi: 10.1073/pnas.81.21.6851.
7
Tunicate Thy-1--an invertebrate member of the Ig superfamily.
Prog Clin Biol Res. 1987;233:33-42.
8
[Construction and expression of mouse-human chimeric Fab fragment gene of monoclonal antibody SZ-2 against platelet].[抗血小板单克隆抗体SZ-2小鼠-人嵌合Fab片段基因的构建与表达]
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2003 Jan;19(1):71-3, 79.
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Mechanisms of tumor growth inhibition.肿瘤生长抑制机制。
Hybridoma. 1986 Jul;5 Suppl 1:S59-64.
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A chimeric antibody with the human gamma1 constant region as a putative standard for assays to detect IgG beta2-glycoprotein I-dependent anticardiolipin and anti-beta2-glycoprotein I antibodies.一种以人γ1恒定区为推定标准的嵌合抗体,用于检测IgGβ2糖蛋白I依赖性抗心磷脂和抗β2糖蛋白I抗体的检测方法。
Arthritis Rheum. 1999 Nov;42(11):2461-70. doi: 10.1002/1529-0131(199911)42:11<2461::AID-ANR25>3.0.CO;2-O.

引用本文的文献

1
Induction of an immune network cascade in cancer patients treated with monoclonal antibodies (ab1). I. May induction of ab1-reactive T cells and anti-anti-idiotypic antibodies (ab3) lead to tumor regression after mAb therapy?单克隆抗体(ab1)治疗癌症患者时免疫网络级联反应的诱导。I. 单克隆抗体治疗后,ab1反应性T细胞和抗抗独特型抗体(ab3)的诱导是否会导致肿瘤消退?
Cancer Immunol Immunother. 1993 Sep;37(4):264-70. doi: 10.1007/BF01518521.
2
Induction of an immune network cascade in cancer patients treated with monoclonal antibodies (ab1). II. Is induction of anti-idiotype reactive T cells (T3) of importance for tumor response to mAb therapy?单克隆抗体(ab1)治疗癌症患者中免疫网络级联反应的诱导。II. 抗独特型反应性T细胞(T3)的诱导对肿瘤对单克隆抗体治疗的反应是否重要?
Cancer Immunol Immunother. 1994 Mar;38(3):149-59. doi: 10.1007/BF01525635.
3
Granulocyte/macrophage-colony-stimulating factor augments the induction of antibodies, especially anti-idiotypic antibodies, to therapeutic monoclonal antibodies.粒细胞/巨噬细胞集落刺激因子增强对治疗性单克隆抗体的抗体诱导,尤其是抗独特型抗体的诱导。
Cancer Immunol Immunother. 1995 Jun;40(6):367-75. doi: 10.1007/BF01525387.
4
Cytotoxicity of white blood cells activated by granulocyte-colony-stimulating factor, granulocyte/macrophage-colony-stimulating factor and macrophage-colony-stimulating factor against tumor cells in the presence of various monoclonal antibodies.在多种单克隆抗体存在的情况下,粒细胞集落刺激因子、粒细胞/巨噬细胞集落刺激因子和巨噬细胞集落刺激因子激活的白细胞对肿瘤细胞的细胞毒性。
Cancer Immunol Immunother. 1994 Oct;39(4):254-62. doi: 10.1007/BF01525989.
5
Comparison of the effector functions of human immunoglobulins using a matched set of chimeric antibodies.使用一组匹配的嵌合抗体比较人免疫球蛋白的效应器功能。
J Exp Med. 1987 Nov 1;166(5):1351-61. doi: 10.1084/jem.166.5.1351.
6
Chimeric mouse-human IgG1 antibody that can mediate lysis of cancer cells.可介导癌细胞裂解的嵌合型小鼠-人IgG1抗体。
Proc Natl Acad Sci U S A. 1987 May;84(10):3439-43. doi: 10.1073/pnas.84.10.3439.
7
Granulocyte-monocyte colony-stimulating-factor augments the interleukin-2-induced cytotoxic activity of human lymphocytes in the absence and presence of mouse or chimeric monoclonal antibodies (mAb 17-1A).在不存在和存在小鼠或嵌合单克隆抗体(mAb 17-1A)的情况下,粒细胞-单核细胞集落刺激因子增强白细胞介素-2诱导的人淋巴细胞的细胞毒性活性。
Cancer Immunol Immunother. 1990;31(4):231-5. doi: 10.1007/BF01789174.