Ortega-Morales Natalia B, Cueto-Wong Jose A, Velez-Monroy Leonardo I, Chavez-Solis Adan U, Barrientos-Juarez Eutiquio, Duarte-Sustaita Jesús Jaime, Veliz-Deras Francisco G, Calderon-Leyva Guadalupe, Moran-Martinez Javier
Autonomous Agrarian University Antonio Narro, Torreón 27054, Coahuila, Mexico.
National Institute of Forest, Agricultural and Livestock Research, La Laguna Experimental Field, Matamoros 27440, Coahuila, Mexico.
Animals (Basel). 2023 Jun 21;13(13):2055. doi: 10.3390/ani13132055.
This study was to evaluate whether selenium and vitamin-E counteract the toxic effects of arsenic on reproductive aspects and physiological conditions of male goats. Male goats [Criollo, = 20, 4-5 yr-old, 72 kg live weight (LW)] were distributed in homogeneous groups ( = 5), and received during 12 weeks: (1) Sodium arsenite 2 mg/kg of LW/day (AG, LW = 69 kg); (2) Sodium selenite 6 mg + vitamin-E 420 I.U. every 14 days during the 12 weeks (SG, LW = 68 kg); (3) Both AG and SG treatments (ASG, LW = 77 kg); and (4) 1 mL of physiological solution every 14 days during the 12 weeks (CG, LW = 72 kg). The animals had access to water from a well with a concentration of 35 μg/L of arsenic. The SG had the highest percentage of sperm viability (80.6%) followed by the CG, ASG (74.7; > 0.05), and AG (64.3; ≤ 0.05). The ASG and SG had a lower heart rate as compared to the CG and AG (58.8, 58 vs. 65.4, 63.5; respectively, ≤ 0.05). The CG and SG showed a lower respiratory rate than the AG and ASG (19.2, 18.7 vs. 22.1, 21.0, respectively; ≤ 0.05). Selenium and vitamin-E were efficient in reducing the damage caused by sodium arsenite in sperm quality and maintaining heart and respiratory rates and increases in odor in male goats.
本研究旨在评估硒和维生素E是否能抵消砷对雄性山羊生殖方面和生理状况的毒性作用。雄性山羊[克里奥罗品种，n = 20，4 - 5岁，体重72千克（LW）]被分成同质组（n = 5），并在12周内接受以下处理：（1）亚砷酸钠2毫克/千克体重/天（AG组，体重 = 69千克）；（2）在12周内每14天给予亚硒酸钠6毫克 + 维生素E 420国际单位（SG组，体重 = 68千克）；（3）同时给予AG组和SG组的处理（ASG组，体重 = 77千克）；以及（4）在12周内每14天给予1毫升生理溶液（CG组，体重 = 72千克）。动物饮用一口砷浓度为35微克/升的井水。SG组精子活力百分比最高（80.6%），其次是CG组、ASG组（74.7%；P > 0.05）和AG组（64.3%；P ≤ 0.05）。与CG组和AG组相比，ASG组和SG组的心率较低（分别为58.8、58次/分钟与65.4、63.5次/分钟；P ≤ 0.05）。CG组和SG组的呼吸频率低于AG组和ASG组（分别为19.2、18.7次/分钟与22.1、21.0次/分钟；P ≤ 0.05）。硒和维生素E在降低亚砷酸钠对精子质量造成的损害、维持雄性山羊的心率和呼吸频率以及减少异味方面是有效的。
