Rodrigues João Victor Soares, Cláudio Marina Módulo, Franciscon João Paulo Soares, Rosa Rossana Abud Cabrera, Cirelli Thamiris, de Molon Rafael Scaf, Figueredo Carlos Marcelo S, Garcia Valdir Gouveia, Theodoro Leticia Helena
Department of Diagnostic and Surgery, School of Dentistry, São Paulo State University (UNESP), Araçatuba 16015-050, SP, Brazil.
Center for Dental Assistance to Persons with Disabilities (CAOE), School of Dentistry, Araçatuba 16015-050, SP, Brazil.
J Clin Med. 2023 Jun 26;12(13):4277. doi: 10.3390/jcm12134277.
We sought to evaluate the effects of non-surgical periodontal treatment (NSPT) on periodontal clinical parameters, systemic blood pressure (BP), and plasma levels of systemic inflammation markers in patients with combined refractory arterial hypertension (RAH) and stage III grade B periodontitis. Twenty-seven participants with RAH and periodontitis received NSPT. The analyzed clinical parameters were probing depth (PD), clinical attachment level (CAL), bleeding on probing (BOP), and plaque index (PI). An assessment was performed for systemic BP, complete blood count, coagulogram, creatinine measurement, C-reactive protein (CRP), glycated hemoglobin, cholesterol, glutamic oxaloacetic transaminase, glutamate pyruvic transaminase, waist-hip ratio, and body mass index. In the follow-up period, twenty-two patients were evaluated at baseline and after 90 and 180 days. The data were submitted for statistical analysis (α = 0.05%). As expected, the clinical results showed a significant improvement in the percentages of PI, BOP, PD, and CAL, which were statistically significant at 90 and 180 days ( < 0.0001). Importantly, NSPT significantly reduced the blood level of CRP ( < 0.02). However, no significant reduction in BP parameters was noted in the evaluated follow-up periods. NSPT, despite the benefits in periodontal clinical parameters, reduced the plasma level of CRP but not the BP in patients with combined RAH and periodontitis.
我们试图评估非手术牙周治疗（NSPT）对合并难治性动脉高血压（RAH）和III期B级牙周炎患者的牙周临床参数、全身血压（BP）和全身炎症标志物血浆水平的影响。27名患有RAH和牙周炎的参与者接受了NSPT。分析的临床参数包括探诊深度（PD）、临床附着水平（CAL）、探诊出血（BOP）和菌斑指数（PI）。对全身血压、全血细胞计数、凝血图、肌酐测量、C反应蛋白（CRP）、糖化血红蛋白、胆固醇、谷草转氨酶、谷丙转氨酶、腰臀比和体重指数进行了评估。在随访期间，对22名患者在基线、90天和180天后进行了评估。数据提交进行统计分析（α = 0.05%）。正如预期的那样，临床结果显示PI、BOP、PD和CAL的百分比有显著改善，在90天和180天时具有统计学意义（<0.0001）。重要的是，NSPT显著降低了CRP的血液水平（<0.02）。然而，在评估的随访期间，未观察到BP参数有显著降低。NSPT尽管对牙周临床参数有益，但在合并RAH和牙周炎的患者中降低了CRP的血浆水平，但未降低BP。
