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一种海藻,具有增强免疫和心脏代谢健康以及调节肠道微生物组成的作用。

: A Seaweed for Enhancing Immune and Cardiometabolic Health and Gut Microbiota Composition Modulation.

机构信息

Escuela de Nutrición y Dietética, Facultad para el Cuidado de la Salud, Universidad San Sebastián, Valdivia 5090000, Chile.

Escuela de Nutrición y Dietética, Facultad de Salud, Universidad Santo Tomás, Puerto Montt 5480000, Chile.

出版信息

Int J Mol Sci. 2023 Jun 28;24(13):10779. doi: 10.3390/ijms241310779.

DOI:10.3390/ijms241310779
PMID:37445955
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10341711/
Abstract

is the seaweed that is the most consumed by the Chilean population. It is recognized worldwide for its high nutritional value in protein, vitamins, minerals, and dietary fiber. This is a narrative review in which an extensive search of the literature was performed to establish the immunomodulator, cardiometabolic, and gut microbiota composition modulation effect of . Several studies have shown the potential of to function as prebiotics and to positively modulate the gut microbiota, which is related to anti-obesity, anti-inflammatory, anticancer, lipid-lowering, and hypoglycemic effects. The quantity of was negatively correlated with that of inflammatory monocytes and positively correlated with the levels of several gut metabolites. Seaweed-derived polysaccharides modulate the quantity and diversity of beneficial intestinal microbiota, decreasing phenol and p-cresol, which are related to intestinal diseases and the loss of intestinal function. Additionally, a beneficial metabolic effect related to this seaweed was observed, mainly promoting the decrease in the glycemic levels, lower cholesterol levels and cardiovascular risk. Consuming has a positive impact on the immune system, and its bioactive compounds provide beneficial effects on glycemic control and other metabolic parameters.

摘要

是智利人消费最多的海藻。它以其在蛋白质、维生素、矿物质和膳食纤维方面的高营养价值而在世界范围内得到认可。这是一篇叙述性综述,对文献进行了广泛搜索,以确定 的免疫调节剂、心脏代谢和肠道微生物群落组成调节作用。几项研究表明, 有作为益生元的潜力,并能积极调节肠道微生物群落,这与抗肥胖、抗炎、抗癌、降血脂和降血糖作用有关。 的数量与炎症性单核细胞的数量呈负相关,与几种肠道代谢物的水平呈正相关。海藻衍生的多糖可调节有益肠道微生物群落的数量和多样性,减少与肠道疾病和肠道功能丧失有关的酚和对甲酚。此外,还观察到与这种海藻有关的有益代谢作用,主要是促进血糖水平降低,胆固醇水平降低和心血管风险降低。食用 对免疫系统有积极影响,其生物活性化合物对血糖控制和其他代谢参数有有益作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b594/10341711/01969ffc808e/ijms-24-10779-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b594/10341711/1beaf2f2ec7c/ijms-24-10779-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b594/10341711/edd402d78418/ijms-24-10779-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b594/10341711/522ab86764af/ijms-24-10779-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b594/10341711/01969ffc808e/ijms-24-10779-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b594/10341711/1beaf2f2ec7c/ijms-24-10779-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b594/10341711/edd402d78418/ijms-24-10779-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b594/10341711/522ab86764af/ijms-24-10779-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b594/10341711/01969ffc808e/ijms-24-10779-g004.jpg

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