Department of Chemical and Pharmaceutical Sciences, University of Trieste, 34127 Trieste, Italy.
Molecules. 2023 Jun 24;28(13):4970. doi: 10.3390/molecules28134970.
Cysteine redox chemistry is widely used in nature to direct protein assembly, and in recent years it has inspired chemists to design self-assembling peptides too. In this concise review, we describe the progress in the field focusing on the recent advancements that make use of Cys thiol-disulfide redox chemistry to modulate hydrogelation of various peptide classes.
半胱氨酸氧化还原化学在自然界中被广泛用于指导蛋白质组装，近年来也启发了化学家设计自组装肽。在这篇简明的综述中，我们描述了该领域的进展，重点介绍了最近利用 Cys 巯基-二硫键氧化还原化学来调节各种肽类水凝胶形成的进展。
