Wang Yu, Liu Wanyou, Dong Baozhu, Wang Dong, Nian Yin, Zhou Hongyou
College of Horticulture and Plant Protection, Inner Mongolia Agricultural University, Hohhot 010020, China.
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China.
Plants (Basel). 2023 Jul 7;12(13):2576. doi: 10.3390/plants12132576.
L. has strong allelopathic effects on weeds. However, the allelochemicals with herbicidal activity in L. are still unknown. In this study, we evaluated the activity of allelochemicals isolated from L. based on the germination and growth of model plant Linn., grass weed , and broadleaf weed Additionally, we employed molecular docking to predict the binding of brassicanate A sulfoxide to herbicide targets. The results of this study showed that eight compounds with herbicidal activity were isolated from L., and the predicted results indicated that brassicanate A sulfoxide was stably bound to dihydroxyacid dehydratase, hydroxymethylpyruvate dioxygenase, acetolactate synthase, PYL family proteins and transport inhibitor response 1. This research provides compound sources and a theoretical foundation for the development of natural herbicides.
L. 对杂草具有强烈的化感作用。然而，L. 中具有除草活性的化感物质仍不明确。在本研究中，我们基于模式植物Linn.、禾本科杂草和阔叶杂草的萌发与生长，评估了从L. 中分离出的化感物质的活性。此外，我们采用分子对接来预测亚砜基芸苔酸与除草剂靶标的结合情况。本研究结果表明，从L. 中分离出了8种具有除草活性的化合物，预测结果表明亚砜基芸苔酸与二羟基酸脱水酶、羟甲基丙酮酸双加氧酶、乙酰乳酸合酶、PYL家族蛋白和运输抑制剂响应蛋白1稳定结合。本研究为天然除草剂的开发提供了化合物来源和理论基础。
