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基于多糖的农药聚合物控释系统的研究进展

Research Progress of a Pesticide Polymer-Controlled Release System Based on Polysaccharides.

作者信息

Zhang Zan, Yang Ni, Yu Jie, Jin Shuo, Shen Guangmao, Chen Hanqiu, Yuzhen Nima, Xiang Dong, Qian Kun

机构信息

College of Plant Protection, Southwest University, Chongqing 400715, China.

Institute of Vegetable, Tibet Academy of Agricultural and Animal Husbandry Sciences, Lhasa 850032, China.

出版信息

Polymers (Basel). 2023 Jun 25;15(13):2810. doi: 10.3390/polym15132810.

Abstract

In recent years, with the development of the nanomaterials discipline, many new pesticide drug-carrying systems-such as pesticide nano-metal particles, nano-metal oxides, and other drug-carrying materials-had been developed and applied to pesticide formulations. Although these new drug-loading systems are relatively friendly to the environment, the direct exposure of many metal nanoparticles to the environment will inevitably lead to potential effects. In response to these problems, organic nanomaterials have been rapidly developed due to their high-quality biodegradation and biocompatibility. Most of these organic nanomaterials were mainly polysaccharide materials, such as chitosan, carboxymethyl chitosan, sodium alginate, β-cyclodextrin, cellulose, starch, guar gum, etc. Some of these materials could be used to carry inorganic materials to develop a temperature- or pH-sensitive pesticide drug delivery system. Herein, the pesticide drug-carrying system developed based on polysaccharide materials, such as chitosan, was referred to as the pesticide polymer drug-carrying system based on polysaccharide materials. This kind of drug-loading system could be used to protect the pesticide molecules from harsh environments, such as pH, light, temperature, etc., and was used to develop the function of a sustained release, targeted release of pesticides in the intestine of insects, and achieve the goal of precise application, reduction, and efficiency of pesticides. In this review, the recent progress in the field of polysaccharide-based polymer drug delivery systems for pesticides has been discussed, and suggestions for future development were proposed based on the current situation.

摘要

近年来,随着纳米材料学科的发展,许多新型农药载药系统,如农药纳米金属颗粒、纳米金属氧化物等载药材料,已被开发并应用于农药制剂中。尽管这些新型载药系统对环境相对友好,但许多金属纳米颗粒直接暴露于环境中不可避免地会产生潜在影响。针对这些问题,有机纳米材料因其高质量的生物降解性和生物相容性而得到迅速发展。这些有机纳米材料大多主要是多糖材料,如壳聚糖、羧甲基壳聚糖、海藻酸钠、β-环糊精、纤维素、淀粉、瓜尔胶等。其中一些材料可用于负载无机材料,开发温度或pH敏感型农药给药系统。在此,基于壳聚糖等多糖材料开发的农药载药系统被称为基于多糖材料的农药聚合物载药系统。这种载药系统可用于保护农药分子免受pH、光、温度等恶劣环境的影响,并用于开发在昆虫肠道中农药的缓释、靶向释放功能,实现农药精准施用、减量增效的目标。在本综述中,讨论了基于多糖的聚合物农药给药系统领域的最新进展,并根据当前情况对未来发展提出了建议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fcf/10346294/473664d6a047/polymers-15-02810-g001.jpg

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