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基于织物的电化学葡萄糖传感器,具有集成的微流控通道,采用疏水的蜡染蜡。

Fabric-Based Electrochemical Glucose Sensor with Integrated Millifluidic Path from a Hydrophobic Batik Wax.

机构信息

School of Electrical Engineering and Informatics, Bandung Institute of Technology, Bandung 40132, Indonesia.

Research Center for Nanosciences and Nanotechnology (RCNN), Bandung Institute of Technology, Bandung 40132, Indonesia.

出版信息

Sensors (Basel). 2023 Jun 22;23(13):5833. doi: 10.3390/s23135833.

DOI:10.3390/s23135833
PMID:37447683
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10346911/
Abstract

In recent years, measuring and monitoring analyte concentrations continuously, frequently, and periodically has been a vital necessity for certain individuals. We developed a cotton-based millifluidic fabric-based electrochemical device (mFED) to monitor glucose continuously and evaluate the effects of mechanical deformation on the device's electrochemical performance. The mFED was fabricated using stencil printing (thick film method) for patterning the electrodes and wax-patterning to make the reaction zone. The analytical performance of the device was carried out using the chronoamperometry method at a detection potential of -0.2 V. The mFED has a linear working range of 0-20 mM of glucose, with LOD and LOQ of 0.98 mM and 3.26 mM. The 3D mFED shows the potential to be integrated as a wearable sensor that can continuously measure glucose under mechanical deformation.

摘要

近年来,对于某些人来说,连续、频繁和定期测量和监测分析物浓度已成为一项至关重要的需求。我们开发了一种基于棉的毫升级织物基电化学装置(mFED),以连续监测葡萄糖并评估机械变形对设备电化学性能的影响。mFED 通过模板印刷(厚膜法)用于对电极进行图案化,并使用蜡图案化来制作反应区。该设备的分析性能是通过在检测电位为-0.2 V 时使用计时安培法进行的。mFED 的线性工作范围为 0-20 mM 的葡萄糖,其检测限和定量限分别为 0.98 mM 和 3.26 mM。3D mFED 显示出作为一种可在机械变形下连续测量葡萄糖的可穿戴传感器进行集成的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9683/10346911/610814336381/sensors-23-05833-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9683/10346911/bf1faea4fc8e/sensors-23-05833-g0A1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9683/10346911/fb6337b6d0d4/sensors-23-05833-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9683/10346911/3134f9621b47/sensors-23-05833-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9683/10346911/d68fcdfaf964/sensors-23-05833-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9683/10346911/74252d8af4e2/sensors-23-05833-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9683/10346911/da4c4d76a502/sensors-23-05833-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9683/10346911/46fa7557be12/sensors-23-05833-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9683/10346911/ec2c389d76b6/sensors-23-05833-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9683/10346911/610814336381/sensors-23-05833-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9683/10346911/bf1faea4fc8e/sensors-23-05833-g0A1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9683/10346911/fb6337b6d0d4/sensors-23-05833-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9683/10346911/3134f9621b47/sensors-23-05833-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9683/10346911/d68fcdfaf964/sensors-23-05833-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9683/10346911/74252d8af4e2/sensors-23-05833-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9683/10346911/da4c4d76a502/sensors-23-05833-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9683/10346911/46fa7557be12/sensors-23-05833-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9683/10346911/ec2c389d76b6/sensors-23-05833-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9683/10346911/610814336381/sensors-23-05833-g008.jpg

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