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坚果摄入与老年人虚弱的关系:一项大型样本横断面研究。

Association between nut consumption and frailty in the elderly: a large sample cross-sectional study.

机构信息

The Second Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China.

Department of Nephrology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China.

出版信息

J Hum Nutr Diet. 2023 Oct;36(5):1845-1856. doi: 10.1111/jhn.13208. Epub 2023 Jul 13.

Abstract

BACKGROUND

Limited literature has addressed the impact of nut consumption in mitigating frailty. This study aimed to investigate the association between nut consumption and frailty among Americans aged above 60 years, employing two 24-h dietary recalls for analysis.

METHODS

The data sets of the National Health and Nutrition Examination Survey (NHANES) (2003-2018) and the Food Patterns Equivalents Database were utilised for a weighted multiple logistic regression model to evaluate the association between nut consumption and frailty in elderly adults. Furthermore, a restricted cubic spline model was employed to investigate the nonlinear relationship between nut intake and frailty. Besides, stratified and interaction analyses were conducted to explore the sensitivity of nut consumption in reducing the risk of frailty in diverse subgroups.

RESULTS

The research study comprised 10,033 individuals aged 60 years or above, of whom 3591 were classified as frailty and 5302 consumed nuts. In the multivariate logistic regression analysis that adjusted for covariates, the weighted multivariate adjusted odds ratios demonstrated that the prevalence of frailty was lower in the nut intake group than in nonconsumers. The stratified analysis indicated that nearly all subgroups who consumed nuts had a significantly lower risk of frailty compared to nonconsumers, and an interaction was observed between nut intake and nonhypertensive populations. The optimal threshold for nut intake to decrease the risk of frailty was identified as 1.02 ounces.

CONCLUSIONS

The study concluded that nut consumption has a constructive impact on averting frailty in elderly adults, particularly in nonhypertensive individuals. Nut intake of ~1.02 ounces per day is advantageous in improving the quality of life in elderly adults.

摘要

背景

关于坚果摄入对衰弱的缓解作用,相关文献十分有限。本研究旨在通过两次 24 小时膳食回顾分析,调查美国 60 岁以上人群中坚果摄入与衰弱的关系。

方法

利用国家健康和营养检查调查(NHANES)(2003-2018 年)和食物模式等效数据库的数据组,采用加权多逻辑回归模型评估老年人中坚果消费与衰弱之间的关系。此外,采用限制立方样条模型探讨坚果摄入量与衰弱之间的非线性关系。另外,还进行了分层和交互分析,以探讨不同亚组中坚果消费降低衰弱风险的敏感性。

结果

本研究纳入了 10033 名 60 岁或以上的个体,其中 3591 名被诊断为衰弱,5302 名食用坚果。在调整了协变量的多变量逻辑回归分析中,加权多变量调整后比值比表明,坚果摄入组的衰弱患病率低于非食用组。分层分析表明,几乎所有食用坚果的亚组与非食用者相比,衰弱的风险显著降低,且坚果摄入与非高血压人群之间存在交互作用。坚果摄入降低衰弱风险的最佳阈值被确定为 1.02 盎司。

结论

研究表明,坚果摄入对老年人预防衰弱具有积极影响,尤其对非高血压人群更为显著。每天摄入约 1.02 盎司的坚果有利于改善老年人的生活质量。

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