Adhikary Rajnandini, Mohan Prerna, Wadhawan Amit, Tyagi Prashant
Department of Periodontology, Shree Bankey Bihari Dental College and Research Centre, Ghaziabad, IND.
Cureus. 2023 Jun 14;15(6):e40435. doi: 10.7759/cureus.40435. eCollection 2023 Jun.
Objective This study set out to examine the results of microneedling (MN) with and without injectable platelet-rich fibrin (i-PRF) in treating individuals with thin periodontal phenotypes, specifically focusing on the effects on gingival thickness (GT) and keratinized tissue width (KTW). Materials and methods This was a split-mouth study involving 32 healthy patients with 64 sites having thin phenotypes classified into two groups. On the one side, i-PRF was injected (Group A), while on the other side (Group B), MN along with i-PRF was used at intervals of 10 days for a month. GT and KTW were measured at baseline, three months, and six months. The parameters were compared intra and intergroup-wise at baseline, three months, and six months using the IBM SPSS Statistics software version 24 (IBM Corp., Armonk, NY) and the chi-square test. Results The findings revealed that when comparing Group A, which received just i-PRF, to Group B, which had i-PRF in conjunction with MN, there was a statistically significant increase in GT in Group B. Conclusions This is a novel method in that it does not need surgical innervations to expand the gingiva in breadth or thickness. Although MN's neoangiogenesis impact contributed to thicker gingiva, i-PRF showed a greater capacity for the release of several growth factors.
目的 本研究旨在探讨微针治疗(MN)联合或不联合注射用富血小板纤维蛋白(i-PRF)治疗牙周组织菲薄型个体的效果,特别关注其对牙龈厚度(GT)和角化组织宽度(KTW)的影响。材料和方法 这是一项双侧对照研究,纳入32例健康患者,共64个牙周组织菲薄型位点,分为两组。一侧注射i-PRF(A组),另一侧(B组)采用微针治疗联合i-PRF,每隔10天治疗1次,共治疗1个月。在基线、3个月和6个月时测量GT和KTW。使用IBM SPSS Statistics软件24版(IBM公司,纽约州阿蒙克)和卡方检验对基线、3个月和6个月时的参数进行组内和组间比较。结果 研究结果显示,仅接受i-PRF治疗的A组与接受i-PRF联合微针治疗的B组相比,B组的GT有统计学意义的增加。结论 这是一种新方法,无需手术干预即可在宽度或厚度上扩展牙龈。虽然微针治疗的新生血管形成作用有助于牙龈增厚,但i-PRF显示出更强的多种生长因子释放能力。