School of Biomedical Sciences, The University of Western Australia, Perth, Western Australia, Australia.
Colorectal Cancer Unit, St John of God Subiaco Hospital, Perth, Western Australia, Australia.
J Surg Oncol. 2024 Jan;129(1):71-77. doi: 10.1002/jso.27400. Epub 2023 Jul 17.
Metachronous colorectal cancer (CRC) metastasis occurs due to micrometastatic disease, in up to 23% of patients who have undergone curative-intent treatment. Metachronous metastasis tends to occur within 2 years of initial treatment. Diagnosis relies on posttreatment surveillance strategies. Care for patients with metachronous CRC metastasis is complex and requires careful multidisciplinary consideration. Those with isolated and technically resectable diseases are recommended to undergo metastasectomy with adjunct chemotherapy, however, survival, even after curative-intent resection, is poor.
异时性结直肠癌（CRC）转移是由于微转移疾病引起的，在接受根治性治疗的患者中，高达 23%的患者会发生这种情况。异时性转移往往发生在初始治疗后 2 年内。诊断依赖于治疗后的监测策略。对异时性 CRC 转移患者的治疗较为复杂，需要仔细的多学科考虑。对于那些孤立的和技术上可切除的疾病，建议进行转移瘤切除术联合辅助化疗，但即使进行了根治性切除，生存情况仍较差。
