小鼠β-干扰素的内化及向细胞核的转运
Internalization and transport of mouse beta-interferon into the cell nucleus.
作者信息
Kushnaryov V M, MacDonald H S, Debruin J, Lemense G P, Sedmak J J, Grossberg S E
出版信息
J Interferon Res. 1986 Jun;6(3):241-5. doi: 10.1089/jir.1986.6.241.
PMID:3745987
Abstract
An electron microscopic technique employing postembedding immunolabeling was used to identify unmodified, intracellular MuIFN-beta molecules. The MuIFN-beta was rapidly internalized by receptor-dependent endocytosis and within three minutes a majority of internalized MuIFN-beta molecules was detected within the cell nucleus.
摘要
采用包埋后免疫标记的电子显微镜技术来鉴定未修饰的细胞内鼠干扰素-β分子。鼠干扰素-β通过受体依赖性内吞作用迅速内化，三分钟内，大部分内化的鼠干扰素-β分子在细胞核内被检测到。
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