纽约长岛萨福克县居住的拉丁裔人群中查加斯病的血清流行率。
Seroprevalence of Chagas Disease among People of Latin American Descent Living in Suffolk County, Long Island, New York.
机构信息
Division of Infectious Diseases, Department of Internal Medicine, Stony Brook University, Stony Brook, New York.
Division of Cardiology, Department of Internal Medicine, Stony Brook University, Stony Brook, New York.
出版信息
Am J Trop Med Hyg. 2023 Jul 17;109(2):319-321. doi: 10.4269/ajtmh.23-0258. Print 2023 Aug 2.
This cross-sectional study estimated a one-time point seroprevalence rate of Chagas disease among people of Latin American descent in Suffolk County, Long Island, New York. Subjects who met the inclusion criteria were screened using the Chagas Detect Plus Rapid Test (InBios, Seattle, WA) with confirmation via Trypanosoma cruzi enzyme immunoassay and T. cruzi immunoblot assay. Administration of a questionnaire regarding demographics and risk factors followed. A seroprevalence rate of 10.74% was found. Identified risk factors included prior residence in a palm leaf house (odds ratio [OR], 10.42; P = 0.003; 95% CI, 2.18-49.76), residence in a house with triatomines (OR, 9.03; P = 0.006; 95% CI, 1.90-42.88), and history of triatomine bite (OR, 9.52; P = 0.009; 95% CI, 1.75-51.77). Our findings emphasize the importance of this frequently underdiagnosed disease and help highlight the importance of early screening among high-risk populations.
本横断面研究估计了纽约长岛萨福克县拉丁裔人群中恰加斯病的单次血清阳性率。符合纳入标准的受试者使用 Chagas Detect Plus 快速检测试剂盒（InBios，西雅图，WA）进行筛查，并用克氏锥虫酶免疫测定法和克氏锥虫免疫印迹法进行确认。随后进行了一份关于人口统计学和危险因素的问卷。发现的血清阳性率为 10.74%。确定的危险因素包括曾居住在棕榈叶屋（比值比[OR]，10.42；P=0.003；95%置信区间，2.18-49.76）、居住在有三锥虫的房屋（OR，9.03；P=0.006；95%置信区间，1.90-42.88）以及三锥虫叮咬史（OR，9.52；P=0.009；95%置信区间，1.75-51.77）。我们的研究结果强调了这种经常被低估的疾病的重要性，并有助于强调在高危人群中进行早期筛查的重要性。
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