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亚甲蓝与自体血混合在肺结节和肿块术前定位中的应用

Utility of methylene blue mixed with autologous blood in preoperative localization of pulmonary nodules and masses.

作者信息

Feng Zhi, Liao Qiu-Xia, Xie Jin-Bao, Chen Jian-Feng, Qiu Ming-Lian, Li Xu

机构信息

Department of Thoracic Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, 350005, Fujian Province, China.

Department of Critical medicine, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, China.

出版信息

Open Life Sci. 2023 Jul 9;18(1):20220645. doi: 10.1515/biol-2022-0645. eCollection 2023.

DOI:10.1515/biol-2022-0645
PMID:37465103
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10350882/
Abstract

The value of CT-guided puncture with methylene blue mixed with autologous blood in preoperative localization of pulmonary nodules and masses was explored. A total of 113 patients with 146 nodules and masses were treated with methylene blue mixed with autologous blood for preoperative localization and thoracoscopic surgery in the Department of Thoracic Surgery, the First Affiliated Hospital of Fujian Medical University between October 2021 and October 2022. The localization effect, complications, and pathological conditions were observed. The localization success rate was 98.63% (144/146). The localization failed nodules and masses could still be located by looking for needle eyes and reading films. The whole group successfully completed thoracoscopic surgery. The average interval of operation after puncture was 22.16 ± 6.22 h. There was a small amount of suspicious hemothorax after puncture. There was no pneumothorax after puncture in the whole group. There were no hemoptysis, irritating dry cough, and other reactions. The overall complication rate was 2.65%, and no special treatment was given. It is safe and effective to use methylene blue mixed with autologous blood for CT-guided preoperative puncture and localization of small pulmonary nodules and masses.

摘要

探讨CT引导下亚甲蓝混合自体血穿刺在肺结节及肿块术前定位中的价值。2021年10月至2022年10月,福建医科大学附属第一医院胸外科对113例患者的146个结节及肿块采用亚甲蓝混合自体血进行术前定位并接受胸腔镜手术,观察定位效果、并发症及病理情况。定位成功率为98.63%(144/146),定位失败的结节及肿块通过寻找针眼及阅片仍可定位。全组均成功完成胸腔镜手术,穿刺后平均手术间隔时间为22.16±6.22小时。穿刺后有少量可疑血胸,全组穿刺后无气胸,无咯血、刺激性干咳等反应,总体并发症发生率为2.65%,未给予特殊处理。CT引导下采用亚甲蓝混合自体血进行小肺结节及肿块术前穿刺定位安全有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e419/10350882/f293d46e647c/j_biol-2022-0645-fig001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e419/10350882/f293d46e647c/j_biol-2022-0645-fig001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e419/10350882/f293d46e647c/j_biol-2022-0645-fig001.jpg

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