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纳洛酮可逆转的急性呼吸衰竭中的横贯性脊髓炎——病例报告

Transverse Myelitis in Naloxone Reversible Acute Respiratory Failure-A Case Report.

作者信息

Dodson Chance, Gentges Joshua

机构信息

University of Oklahoma, Department of Emergency Medicine, Tulsa, OK.

出版信息

J Educ Teach Emerg Med. 2022 Oct 15;7(4):V15-V18. doi: 10.21980/J8B659. eCollection 2022 Oct.

DOI:10.21980/J8B659
PMID:37465136
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10332668/
Abstract

UNLABELLED

Transverse myelitis (TM) is a rare inflammatory myelopathy presenting as bilateral neurologic deficit localized to the spinal cord. A critical management step in the emergency department (ED) is evaluating for and treating acute reversible causes such as mass lesion or reversible ischemia when present. Described in this case report is TM presenting after a respiratory arrest in suspected opioid overdose. Magnetic resonance imaging (MRI), ideally with contrast, and lumbar puncture are essential diagnostic studies to confirm inflammation. Finally, further diagnostic efforts are aimed at evaluation and treatment for other concurrent illnesses.

TOPICS

Transverse myelitis, transverse myelopathy, hypoxia, opioid overdose, hypoxic spinal cord injury.

摘要

未标注

横贯性脊髓炎(TM)是一种罕见的炎症性脊髓病,表现为局限于脊髓的双侧神经功能缺损。急诊科(ED)的关键管理步骤是评估并治疗急性可逆性病因,如存在占位性病变或可逆性缺血时。本病例报告描述了疑似阿片类药物过量导致呼吸骤停后出现的横贯性脊髓炎。磁共振成像(MRI)(理想情况下需增强扫描)和腰椎穿刺是确诊炎症的重要诊断性检查。最后,进一步的诊断工作旨在评估和治疗其他并发疾病。

主题

横贯性脊髓炎、横贯性脊髓病、缺氧、阿片类药物过量、缺氧性脊髓损伤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c78d/10332668/8a6b696f76c0/jetem-7-4-v15f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c78d/10332668/8a6b696f76c0/jetem-7-4-v15f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c78d/10332668/8a6b696f76c0/jetem-7-4-v15f1.jpg

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Transverse Myelitis in Naloxone Reversible Acute Respiratory Failure-A Case Report.纳洛酮可逆转的急性呼吸衰竭中的横贯性脊髓炎——病例报告
J Educ Teach Emerg Med. 2022 Oct 15;7(4):V15-V18. doi: 10.21980/J8B659. eCollection 2022 Oct.
2
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本文引用的文献

1
Adverse events related to bystander naloxone administration in cases of suspected opioid overdose in British Columbia: An observational study.不列颠哥伦比亚省疑似阿片类药物过量病例中旁观者纳洛酮给药相关不良事件:一项观察性研究。
PLoS One. 2021 Oct 29;16(10):e0259126. doi: 10.1371/journal.pone.0259126. eCollection 2021.
2
Signal of increased opioid overdose during COVID-19 from emergency medical services data.从紧急医疗服务数据看 COVID-19 期间阿片类药物过量的信号增加。
Drug Alcohol Depend. 2020 Sep 1;214:108176. doi: 10.1016/j.drugalcdep.2020.108176. Epub 2020 Jul 10.
3
Characteristics of Spontaneous Spinal Cord Infarction and Proposed Diagnostic Criteria.
自发性脊髓梗死的特征及诊断标准建议。
JAMA Neurol. 2019 Jan 1;76(1):56-63. doi: 10.1001/jamaneurol.2018.2734.
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Evaluation of idiopathic transverse myelitis revealing specific myelopathy diagnoses.评估特发性横贯性脊髓炎揭示特定的脊髓病诊断。
Neurology. 2018 Jan 9;90(2):e96-e102. doi: 10.1212/WNL.0000000000004796. Epub 2017 Dec 15.
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Heroin-induced acute longitudinally extensive transverse myelopathy.海洛因所致急性长节段横贯性脊髓病
Neurol Sci. 2018 Apr;39(4):791-792. doi: 10.1007/s10072-017-3197-x. Epub 2017 Nov 17.
6
Recrudescence of Deficits After Stroke: Clinical and Imaging Phenotype, Triggers, and Risk Factors.中风后功能缺损的复发:临床及影像学表型、触发因素和危险因素
JAMA Neurol. 2017 Sep 1;74(9):1048-1055. doi: 10.1001/jamaneurol.2017.1668.
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International consensus diagnostic criteria for neuromyelitis optica spectrum disorders.视神经脊髓炎谱系障碍国际共识诊断标准
Neurology. 2015 Jul 14;85(2):177-89. doi: 10.1212/WNL.0000000000001729. Epub 2015 Jun 19.
8
Transverse myelitis.横贯性脊髓炎。
Neurol Clin. 2013 Feb;31(1):79-138. doi: 10.1016/j.ncl.2012.09.008.
9
Unusual complications of heroin abuse: transverse myelitis, rhabdomyolysis, compartment syndrome, and ARF.海洛因滥用的罕见并发症:横贯性脊髓炎、横纹肌溶解症、骨筋膜室综合征和急性肾衰竭。
Clin Toxicol (Phila). 2008 Feb;46(2):153-5. doi: 10.1080/15563650701639071.
10
Adverse events after naloxone treatment of episodes of suspected acute opioid overdose.纳洛酮治疗疑似急性阿片类药物过量发作后的不良事件。
Eur J Emerg Med. 2004 Feb;11(1):19-23. doi: 10.1097/00063110-200402000-00004.