Bedder Marshall, Parker Lisa
Department of Surgery, Pain Medicine Service, Charlie Norwood Veterans Administration Medical Center, Augusta, GA, USA.
Department of Psychiatry and Health Behavior, Addiction Medicine Service, Medical College of Georgia at Augusta University, Augusta, GA, USA.
J Pain Res. 2023 Jul 12;16:2365-2373. doi: 10.2147/JPR.S409331. eCollection 2023.
To assess magnetic peripheral nerve stimulation (mPNS) for the treatment of chronic or chronic and intractable neuropathic pain with a retrospective review case series.
Twenty-four patients with predominantly neuropathic post-traumatic or postoperative pain were treated as per protocol and followed for 3 months.
Data were analyzed as an observational, one-armed, convenience sample. Graphical evidence backed up by a mixed model for repeated measures statistical analysis showed a highly significant reduction of pain at one month out from initial treatment with mPNS. At one month, there was a 3.8 average reduction in pre-pain scores using a visual analogue scale (VAS), and that relief was generally durable measured out to three months. Two-thirds of patients, deemed responders, showed an 87% reduction in pain. Opioid reduction was seen in 58.3% of responders as well.
mPNS appears promising for the treatment of chronic or chronic and intractable neuropathic pain for many of the same indications as traditional electrical peripheral nerve stimulation (PNS). No invasive techniques or implants are needed for mPNS.
通过回顾性病例系列研究评估磁外周神经刺激（mPNS）治疗慢性或慢性难治性神经性疼痛的效果。
24例主要为创伤后或术后神经性疼痛的患者按方案接受治疗，并随访3个月。
数据作为观察性、单臂、便利样本进行分析。重复测量统计分析的混合模型支持的图形证据显示，在首次使用mPNS治疗1个月后疼痛显著减轻。1个月时，使用视觉模拟量表（VAS）测量，疼痛前评分平均降低3.8分，且这种缓解通常持续到3个月。三分之二的患者被视为有反应者，疼痛减轻了87%。58.3%的有反应者也减少了阿片类药物的使用。
对于许多与传统电外周神经刺激（PNS）相同的适应症，mPNS在治疗慢性或慢性难治性神经性疼痛方面似乎很有前景。mPNS不需要侵入性技术或植入物。
