Institut National de la Santé et de la Recherche Médicale, Centre de Recherche des Cordeliers, Sorbonne Université, Université de Paris, 75006 Paris, France.
Institut National de la Santé et de la Recherche Médicale, Centre de Recherche des Cordeliers, Sorbonne Université, Université de Paris, 75006 Paris, France; Department of Biological Sciences & Engineering, Indian Institute of Technology Palakkad, Palakkad 678623, India.
Cell Rep Med. 2023 Jul 18;4(7):101117. doi: 10.1016/j.xcrm.2023.101117.
Severe obesity accelerates the decline of neutralizing antibodies to COVID-19 vaccines contributing to increased risk of hospitalization from breakthrough SARS-CoV-2 infections. These findings have repercussion on the vaccination policy for SARS-CoV-2 variants and other infectious diseases like influenza in obese population.
严重肥胖加速了对 COVID-19 疫苗的中和抗体的衰减,增加了突破性 SARS-CoV-2 感染导致住院的风险。这些发现对 SARS-CoV-2 变异株和肥胖人群中流感等其他传染病的疫苗接种政策产生了影响。