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髋臼和骨盆环骨折患者的静脉血栓栓塞时间。

Timing of venous thromboemboli in patients with acetabular and pelvic ring fractures.

机构信息

University of Mississippi Medical Center, 2500 N State Street, Jackson, MS, 39216, USA.

Oschner Lafayette General Orthopedic Center, 4212 W Congress St. Ste. 3100, Lafayette, LA, 70506, USA.

出版信息

Eur J Orthop Surg Traumatol. 2024 Oct;34(7):3483-3490. doi: 10.1007/s00590-023-03643-6. Epub 2023 Jul 19.

Abstract

PURPOSE

To determine the timing of symptomatic venous thromboemboli (VTE) in patients sustaining a pelvic and/or acetabular fracture. Secondly, to evaluate for any factors that may influence this timing.

METHODS

A retrospective cohort of 47 patients with acetabular and/or pelvic ring injuries who developed VTEs at a single academic level I trauma center were identified from 2012 to 2018. The chronology of VTE diagnosis in relation to date of injury, initial surgery, final surgery, and date of discharge was evaluated. Patients who developed VTEs were then evaluated based on known risk factors for VTE to determine if any of these affected timing.

RESULTS

Symptomatic VTEs were diagnosed in 3.8% of patients with pelvic and/or acetabular fractures. In patients who developed a thromboembolism, diagnosis occurred on average 21.5 (± 19.2), 20.7 (± 19.9), 9.8 (± 23.4), and 4.3 (± 27.6) days after injury, index procedure, final procedure, and date of discharge. 25% of patients developed VTE more than 4 weeks after their initial injury. No known risk factors effected the timing of VTE.

CONCLUSION

The 2015 OTA expert panel recommends 4 weeks of anticoagulation for orthopedic trauma patients at high risk of VTE, which may be too short a duration. In our cohort, 25% of VTEs occurred greater than 4 weeks after injury. Additional research is needed to clarify the exact duration of anticoagulation after pelvic and acetabular fractures; however, surgeons may want to consider anticoagulating patients for greater than 4 weeks.

LEVEL OF EVIDENCE

Level III-retrospective cohort.

摘要

目的

确定骨盆和/或髋臼骨折患者发生症状性静脉血栓栓塞症(VTE)的时间。其次,评估可能影响这种时间的任何因素。

方法

从 2012 年至 2018 年,在一家学术一级创伤中心,对 47 例髋臼和/或骨盆环损伤患者的回顾性队列进行了研究,这些患者发生了 VTE。评估 VTE 诊断与损伤日期、初始手术、最终手术和出院日期的时间关系。然后根据 VTE 的已知危险因素评估发生 VTE 的患者,以确定是否存在任何影响时间的因素。

结果

3.8%的骨盆和/或髋臼骨折患者诊断出症状性 VTE。在发生血栓栓塞的患者中,诊断平均发生在损伤后 21.5(±19.2)、20.7(±19.9)、9.8(±23.4)和 4.3(±27.6)天、索引手术、最终手术和出院日期。25%的患者在初始损伤后 4 周以上发生 VTE。没有已知的危险因素影响 VTE 的时间。

结论

2015 年 OTA 专家小组建议对高 VTE 风险的骨科创伤患者进行 4 周的抗凝治疗,这可能太短了。在我们的队列中,25%的 VTE 发生在损伤后 4 周以上。需要进一步的研究来明确骨盆和髋臼骨折后抗凝的确切持续时间;然而,外科医生可能需要考虑对患者进行超过 4 周的抗凝治疗。

证据水平

III 级-回顾性队列。

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