Carlson R G, Finley R K, Miller S F, Jones L M, Morath M A, Alkire S
J Trauma. 1986 Sep;26(9):840-3. doi: 10.1097/00005373-198609000-00011.
The quantity of fluid retained during the first 48 hours of resuscitation has been suggested as an indicator of burn severity and mortality (13). In this study of 82 adult burned patients with more than 20% total body surface burns we found that the net fluid retention during the first 48 hours of resuscitation was a predictor of burn mortality and additionally 230 cc of retained fluid per kilogram of lean body mass in the initial 48 hours postburn was an excellent means for separating survivors from nonsurvivors. Fluid retention as an indicator of burn severity and mortality was compared to other methods of predicting burned patient mortality. Parameters evaluated included the per cent body surface area burned, per cent full thickness burn, presence or absence of inhalation injuries, sex, age, and ultimate outcome. The Abbreviated Burn Severity Index (ABSI) (14) was determined for each patient using these data. A comparison was made between fluid retention data, per cent body surface area burned, and the calculated Abbreviated Burn Severity Index and patient mortality. The power of each variable to predict mortality was evaluated by stepwise regression analysis. From this analysis net fluid retention during the first 48 hours of resuscitation was as accurate as the Abbreviated Burn Severity Index and was a better predictor of mortality than individual components of that Index.
复苏最初48小时内的液体潴留量已被认为是烧伤严重程度和死亡率的一个指标(13)。在这项对82例成人全身烧伤面积超过20%的烧伤患者的研究中，我们发现复苏最初48小时内的净液体潴留是烧伤死亡率的一个预测指标，此外，烧伤后最初48小时内每千克瘦体重潴留230毫升液体是区分幸存者和非幸存者的一个极佳方法。将作为烧伤严重程度和死亡率指标的液体潴留与其他预测烧伤患者死亡率的方法进行了比较。评估的参数包括烧伤体表面积百分比、全层烧伤百分比、有无吸入性损伤、性别、年龄和最终结局。使用这些数据为每位患者确定简化烧伤严重程度指数(ABSI)(14)。对液体潴留数据、烧伤体表面积百分比、计算出的简化烧伤严重程度指数与患者死亡率进行了比较。通过逐步回归分析评估每个变量预测死亡率的能力。通过该分析，复苏最初48小时内的净液体潴留与简化烧伤严重程度指数一样准确，并且比该指数的各个组成部分更能预测死亡率。
