Tovani-Palone Marcos Roberto, Doshi Neel, Pedersini Paolo
Department of Research Analytics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai 600077, India.
Department of Medicine, Pravara Institute of Medical Sciences, Ahmednagar 413736, India.
World J Clin Cases. 2023 Jul 6;11(19):4498-4503. doi: 10.12998/wjcc.v11.i19.4498.
Monkeypox (mpox) has been a public health emergency of international concern that emerged in mid-2022 and has spread to 110 countries. The clinical findings of the disease vary according to the seriousness of the cases. Although its case fatality risk has not been high, a significant percentage of patients require hospitalization. In this context, local initiatives were taken to extend the limited supply of vaccines against the disease; however, such measures have not been sufficient to contain the spread of cases and ensure an equitable distribution of health resources. As a result, endemic regions of low-income countries continue to have insufficient access to mpox vaccination. Despite this and considering the global scope of the disease, there is still little discussion in the literature about the difficulties in achieving adequate vaccination coverage rates for the target population of interest. In this article, we briefly discussed general aspects of the disease, including its surveillance, the current global context of challenges for mpox vaccination, and issues on global allocation of health resources as well as proposed related recommendations.
猴痘（mpox）自2022年年中出现以来一直是国际关注的突发公共卫生事件，现已传播至110个国家。该疾病的临床症状因病例严重程度而异。尽管其病死率不高，但仍有相当比例的患者需要住院治疗。在此背景下，当地采取了一系列举措来扩大针对该疾病的有限疫苗供应；然而，这些措施仍不足以遏制病例传播并确保卫生资源的公平分配。因此，低收入国家的流行地区在获取猴痘疫苗方面仍然不足。尽管如此，考虑到该疾病的全球范围，文献中关于实现目标人群足够疫苗接种覆盖率所面临困难的讨论仍然很少。在本文中，我们简要讨论了该疾病的一般情况，包括其监测、猴痘疫苗接种当前面临的全球挑战、卫生资源的全球分配问题以及提出的相关建议。
