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全球猴痘疫苗分配与公平获取面临的挑战

Challenges in Global Distribution and Equitable Access to Monkeypox Vaccines.

作者信息

Danladi Nengak P, Agboola Progress, Olaniyi Peter, Eze Solomon, Oladapo Oluwatimilehin, Obiwulu Danielle, Akano Olatokun Shamsudeen, Adeola Olowoyeye Aishat, Olawale Khaliq, Adiatu Azeez Idowu, Peace Agboola

机构信息

Global Health Infectious Diseases and Control Institute, Nasarawa State University Keffi, RWR4+H9P, Keffi 961101, Nigeria.

African Community for Systematic Review and Meta-Analysis, 172 Akai Efa, MCC Road, Calabar 540211, Cross River State, Nigeria.

出版信息

Viruses. 2024 Nov 21;16(12):1815. doi: 10.3390/v16121815.

DOI:10.3390/v16121815
PMID:39772126
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11680248/
Abstract

The monkeypox outbreak has grown beyond the regions in which it was considered endemic. It has spread from central and west Africa to non-endemic regions like Europe, America, and other parts of the world. It has recently been classified as a public health emergency of international concern. This study evaluated the challenges faced globally and equitable access to monkeypox vaccines. Global competition has been observed in the race to obtain vaccines, with low- and middle-income countries being disadvantaged. Great inequity exists in the distribution of vaccines globally through advance purchase agreements, vaccine stockpiling, vaccine nationalism, the inequitable distribution of existing resources, and insufficient surveillance and reporting mechanisms. To address some of these challenges, there is a need for strengthening the global vaccine manufacturing capacity, targeting countries with elevated risk profiles and limited resources, strengthening surveillance systems, and addressing vaccine hesitancy.

摘要

猴痘疫情已蔓延至原本被视为地方病流行区域之外的地区。它已从非洲中部和西部传播到欧洲、美洲及世界其他非地方病流行地区。最近,它被列为国际关注的突发公共卫生事件。本研究评估了全球面临的挑战以及猴痘疫苗的公平可及性。在获取疫苗的竞赛中出现了全球竞争,低收入和中等收入国家处于不利地位。通过预购协议、疫苗储备、疫苗民族主义、现有资源分配不均以及监测和报告机制不足,全球疫苗分配存在巨大不平等。为应对其中一些挑战,有必要加强全球疫苗生产能力,针对风险较高且资源有限的国家,加强监测系统,并解决疫苗犹豫问题。

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本文引用的文献

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Saudi Med J. 2024 Aug;45(9):1002-1003.
2
The Feasibility of Elimination of Monkeypox Virus in Nigeria: A Systematic Review.尼日利亚消除猴痘病毒的可行性:一项系统评价
Cureus. 2024 Jun 7;16(6):e61867. doi: 10.7759/cureus.61867. eCollection 2024 Jun.
3
Third-generation smallpox vaccines induce low-level cross-protecting neutralizing antibodies against Monkeypox virus in laboratory workers.第三代天花疫苗在实验室工作人员中诱导出针对猴痘病毒的低水平交叉保护性中和抗体。
Heliyon. 2024 May 18;10(10):e31490. doi: 10.1016/j.heliyon.2024.e31490. eCollection 2024 May 30.
4
Monkeypox: An outbreak of a rare viral disease.猴痘:一种罕见病毒性疾病的爆发。
J Microbiol Immunol Infect. 2024 Feb;57(1):1-10. doi: 10.1016/j.jmii.2023.12.006. Epub 2023 Dec 28.
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A Review of the Past, Present, and Future of the Monkeypox Virus: Challenges, Opportunities, and Lessons from COVID-19 for Global Health Security.猴痘病毒的过去、现在与未来回顾:挑战、机遇以及新冠疫情给全球卫生安全带来的教训
Microorganisms. 2023 Nov 6;11(11):2713. doi: 10.3390/microorganisms11112713.
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Lancet Infect Dis. 2024 Jan;24(1):57-64. doi: 10.1016/S1473-3099(23)00492-9. Epub 2023 Sep 4.
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