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使用基于双向长短期记忆网络的改进遗传算法在三维计算机断层扫描图像中检测颅内出血

Intracranial hemorrhage detection in 3D computed tomography images using a bi-directional long short-term memory network-based modified genetic algorithm.

作者信息

Sengupta Jewel, Alzbutas Robertas, Falkowski-Gilski Przemysław, Falkowska-Gilska Bożena

机构信息

Kaunas University of Technology, Kaunas, Lithuania.

Faculty of Electronics, Telecommunications and Informatics, Gdansk University of Technology, Gdansk, Poland.

出版信息

Front Neurosci. 2023 Jul 4;17:1200630. doi: 10.3389/fnins.2023.1200630. eCollection 2023.

Abstract

INTRODUCTION

Intracranial hemorrhage detection in 3D Computed Tomography (CT) brain images has gained more attention in the research community. The major issue to deal with the 3D CT brain images is scarce and hard to obtain the labelled data with better recognition results.

METHODS

To overcome the aforementioned problem, a new model has been implemented in this research manuscript. After acquiring the images from the Radiological Society of North America (RSNA) 2019 database, the region of interest (RoI) was segmented by employing Otsu's thresholding method. Then, feature extraction was performed utilizing Tamura features: directionality, contrast, coarseness, and Gradient Local Ternary Pattern (GLTP) descriptors to extract vectors from the segmented RoI regions. The extracted vectors were dimensionally reduced by proposing a modified genetic algorithm, where the infinite feature selection technique was incorporated with the conventional genetic algorithm to further reduce the redundancy within the regularized vectors. The selected optimal vectors were finally fed to the Bi-directional Long Short Term Memory (Bi-LSTM) network to classify intracranial hemorrhage sub-types, such as subdural, intraparenchymal, subarachnoid, epidural, and intraventricular.

RESULTS

The experimental investigation demonstrated that the Bi-LSTM based modified genetic algorithm obtained 99.40% sensitivity, 99.80% accuracy, and 99.48% specificity, which are higher compared to the existing machine learning models: Naïve Bayes, Random Forest, Support Vector Machine (SVM), Recurrent Neural Network (RNN), and Long Short-Term Memory (LSTM) network.

摘要

引言

三维计算机断层扫描(CT)脑图像中的颅内出血检测在研究领域受到了更多关注。处理三维CT脑图像的主要问题是难以获得带有更好识别结果的标记数据。

方法

为克服上述问题,本研究手稿中实现了一种新模型。从北美放射学会(RSNA)2019数据库获取图像后,采用大津阈值法分割感兴趣区域(RoI)。然后,利用田村特征(方向性、对比度、粗糙度)和梯度局部三元模式(GLTP)描述符从分割后的RoI区域提取特征向量。通过提出一种改进的遗传算法对提取的向量进行降维,该算法将无限特征选择技术与传统遗传算法相结合,以进一步减少正则化向量中的冗余。最后,将选定的最优向量输入双向长短期记忆(Bi-LSTM)网络,对颅内出血亚型(如硬膜下、脑实质内、蛛网膜下、硬膜外和脑室内)进行分类。

结果

实验研究表明,基于Bi-LSTM的改进遗传算法获得了99.40%的灵敏度、99.80%的准确率和99.48%的特异性,与现有的机器学习模型(朴素贝叶斯、随机森林、支持向量机(SVM)、递归神经网络(RNN)和长短期记忆(LSTM)网络)相比更高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/abef/10352619/97031da8f1c7/fnins-17-1200630-g001.jpg

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